Evidence map›Paper›PMID 24038814›Full record

ArticleAsia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists2015

Comparing schizophrenia symptoms in the Iban of Sarawak with other populations to elucidate clinical heterogeneity.

Duncan McLean, Robert Barrett, Peter Loa, Rangaswamy Thara, Sujit John, John McGrath, Jake Gratten, Bryan Mowry

Open access · greenAbstract read
In one paragraph

Article in Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Duncan McLeanThe Park - Centre for Mental Health, Queensland Centre for Mental Health Research, Wacol, QLD, Australia.
Robert Barrett
Peter Loa
Rangaswamy Thara
Sujit John
John McGrath
Jake Gratten
Bryan Mowry
Park Centre for Mental Health · AUSchizophrenia Research Foundation · INUniversity of Adelaide · AUQueensland Centre for Mental Health Research · AUUniversity of Queensland · AU

Funding

MOLECULAR GENETICS OF SCHIZOPHRENIAR01MH059588 · NIMH · UNIVERSITY OF QUEENSLAND · PI MOWRY, BRYAN JOHN · 1999 to 2006
$1.4M
NIMH NIH HHS R01 MH059588NIMH NIH HHS R01 MH59588
6 · The paper itself

Abstract

introductionThe symptom profile of schizophrenia can vary between ethnic groups. We explored selected symptom variables previously reported to be characteristic of schizophrenia in the Iban of Sarawak in transethnic populations from Australia, India, and Sarawak, Malaysia. We tested site differences to confirm previous research, and to explore implications of differences across populations for future investigations.

methodsWe recruited schizophrenia samples in Australia (n = 609), India (n = 310) and Sarawak (n = 205) primarily for the purposes of genetic studies. We analyzed seven identified variables and their relationship to site using logistic regression, including: global delusions, bizarre delusions, thought broadcast/insertion/withdrawal delusions, global hallucinations, auditory hallucinations, disorganized behavior, and prodromal duration.

resultsWe identified a distinct symptom profile in our Sarawak sample. Specifically, the Iban exhibit: low frequency of thought broadcast/insertion/withdrawal delusions, high frequency of auditory hallucinations and disorganized behavior, with a comparatively short prodrome when compared with Australian and Indian populations. DISCUSSION: Understanding between-site variation in symptom profile may complement future transethnic genetic studies, and provide important clues as to the nature of differing schizophrenia expression across ethnically distinct groups. A comprehensive approach to subtyping schizophrenia is warranted, utilizing comprehensively ascertained transethnic samples to inform both schizophrenia genetics and nosology.

Indexed as

AdultAustraliaDelusionsFemaleHallucinationsHumansMalaysiaMaleMiddle AgedSchizophreniaSymptom Assessmentculturediagnosispopulation characteristicpsychotic disorderschizophrenia

Identifiers

PMID24038814
PMCPMC3932150
OpenAlexW1509684774

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.