Evidence map›Paper›PMID 24038733›Full record

ArticleAngewandte Chemie (International ed. in English)2013

Folding of 16S rRNA in a signal-producing structure for the detection of bacteria.

Yulia V Gerasimova, Dmitry M Kolpashchikov

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. DNA Nanomachine (DNM) Biplex Assay for DifferentiatingInternational journal of molecular sciences · 2023
    Article
  2. Article
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  8. Magnetic Field-Activated Sensing of mRNA in Living Cells.Journal of the American Chemical Society · 2017
    Article
  9. Article
  10. Article
  11. Article
  12. DNA Antenna Tile-Associated Deoxyribozyme Sensor with Improved Sensitivity.Chembiochem : a European journal of chemical biology · 2016
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Divide and control: split design of multi-input DNA logic gates.Chemical communications (Cambridge, England) · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yulia V GerasimovaChemistry Department, University of Central Florida, 4000 Central Florida Blvd, Orlando, FL 32816 (USA). yugeras@gmail.com.
Dmitry M Kolpashchikov

Funding

Nucleic acid analysis using deoxyribozyme technologyR21HG004060 · NHGRI · UNIVERSITY OF CENTRAL FLORIDA · PI KOLPASHCHIKOV, DMITRY MIKHAYLOVICH · 2006 to 2010
$592k
Deoxyribozyme sensor-based diagnostics for Mycobacterium tuberculosisR15AI103880 · NIAID · UNIVERSITY OF CENTRAL FLORIDA · PI KOLPASHCHIKOV, DMITRY MIKHAYLOVICH · 2013 to 2013
$430k
NHGRI NIH HHS R21 HG004060NIAID NIH HHS R15 AI103880NIAID NIH HHS R15AI10388001A1
6 · The paper itself

Abstract

Sixty-four DNA strands hybridize to 16S rRNA to form 32 deoxyribozyme catalytic cores that produce a fluorescent signal. The approach allows detection of 0.6 pM 16S rRNA, or about 3×10(4) bacterial cells in a PCR-free format.

Indexed as

BacteriaDNA, CatalyticNucleic Acid ConformationRNA, BacterialRNA, Ribosomal, 16SDNA, CatalyticRNA, BacterialRNA, Ribosomal, 16S16S rRNAbinary deoxyribozymedetection of bacteriaDNA origamifluorescent sensors

Identifiers

PMID24038733
PMCPMC3863991

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.