Trial reportDepression and anxiety2013
Sleep quality predicts treatment outcome in CBT for social anxiety disorder.
Trial report in Depression and anxiety, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02325128 (Augmentation of Exposure Therapy for High Levels of Social Anxiety Using Post-exposure Naps), which is not on this map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Augmentation of Exposure Therapy for High Levels of Social Anxiety Using Post-exposure Naps
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- D-Cycloserine in Neuropsychiatric Diseases: A Systematic Review.The international journal of neuropsychopharmacology · 2016Pooled it
- Augmentation of cognitive and behavioural therapies (CBT) with d-cycloserine for anxiety and related disorders.The Cochrane database of systematic reviews · 2015Pooled it
- Do subjective and objective baseline sleep disturbances predict post-traumatic stress disorder treatment response? A secondary analysis of a randomized controlled trial.European journal of psychotraumatology · 2026Trial
- What good are positive emotions for treatment? A replication test of whether trait positive emotionality predicts response to exposure therapy for social anxiety disorder.Behaviour research and therapy · 2023Trial
- Sleep quality and outcome of exposure therapy in adults with social anxiety disorder.Depression and anxiety · 2021Trial
- Sleep quality and treatment of social anxiety disorder.Anxiety, stress, and coping · 2019Trial
- Sleep Quality Improvement During Cognitive Behavioral Therapy for Anxiety Disorders.Behavioral sleep medicine · 2016Trial
- Dose timing of D-cycloserine to augment cognitive behavioral therapy for social anxiety: Study design and rationale.Contemporary clinical trials · 2015Trial
- Sleep dysfunction in social anxiety disorder.The British journal of clinical psychology · 2026Article
- Short-term prospective and reciprocal relations between social anxiety symptoms and sleep quality among community-recruited adolescents.Psychology & health · 2026Observational
- Exploring the association between sleep and fear extinction learning in adolescents with anxiety and/or OCD: a study protocol.Sleep advances : a journal of the Sleep Research Society · 2025Article
- Reported history of childhood trauma, mentalizing deficits, and hypersomnia in adulthood: A mediational analysis in a nonclinical sample.Brain and behavior · 2024Article
- Relationship of sleep-quality and social-anxiety in patients with breast cancer: a network analysis.BMC psychiatry · 2023Article
- Neurocognitive Model of Schema-Congruent and -Incongruent Learning in Clinical Disorders: Application to Social Anxiety and Beyond.Perspectives on psychological science : a journal of the Association for Psychological Science · 2023Article
- Treatment Implications of Sleep-Related Problems in Pediatric Anxiety Disorders: A Narrative Review of the Literature.Child psychiatry and human development · 2023Review
- The future of psychopharmacology: a critical appraisal of ongoing phase 2/3 trials, and of some current trends aiming to de-risk trial programmes of novel agents.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2023Article
- The Impact of Sleep on Fear Extinction.Current topics in behavioral neurosciences · 2023Article
- Sleep Problems, Social Anxiety and Stuttering Severity in Adults Who Do and Adults Who Do Not Stutter.Journal of clinical medicine · 2022Article
- Sleep quality and emotion recognition in individuals with and without internalizing psychopathologies.Journal of behavior therapy and experimental psychiatry · 2022Article
- Targeted Memory Reactivation During REM Sleep in Patients With Social Anxiety Disorder.Frontiers in psychiatry · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
backgroundSleep quality may be an important, yet relatively neglected, predictor of treatment outcome in cognitive-behavioral therapy (CBT) for anxiety disorders. Specifically, poor sleep quality may impair memory consolidation of in-session extinction learning. We therefore examined sleep quality as a predictor of treatment outcome in CBT for social anxiety disorder and the impact of d-cycloserine (DCS) on this relationship.
methodsOne hundred sixty-nine participants with a primary diagnosis of DSM-IV generalized social anxiety disorder were recruited across three sites. Participants were enrolled in 12 weeks of group CBT. Participants randomly received 50 mg of DCS (n = 87) or pill placebo (n = 82) 1 hr prior to sessions 3-7. Participants completed a baseline measure of self-reported sleep quality and daily diaries recording subjective feelings of being rested upon wakening. Outcome measures including social anxiety symptoms and global severity scores were assessed at each session.
resultsPoorer baseline sleep quality was associated with slower improvement and higher posttreatment social anxiety symptom and severity scores. Moreover, patients who felt more "rested" after sleeping the night following a treatment session had lower levels of symptoms and global severity at the next session, controlling for their symptoms and severity scores the previous session. Neither of these effects were moderated by DCS condition.
conclusionsOur findings suggest that poor sleep quality diminishes the effects of CBT for social anxiety disorder and this relation is not attenuated by DCS administration. Therapeutic attention to sleep quality prior to initiation of CBT and during the acute treatment phase may be clinically indicated.
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