ArticleInternational journal of epidemiology2013
Skin cancer as a marker of sun exposure associates with myocardial infarction, hip fracture and death from any cause.
Article in International journal of epidemiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Effects of ultraviolet light exposure on blood pressure: a systematic review.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026Pooled it
- All-cause mortality in patients with basal and squamous cell carcinoma: A systematic review and meta-analysis.Journal of the American Academy of Dermatology · 2018Pooled it
- Nonmelanoma skin cancer and risk of all-cause and cancer-related mortality: a systematic review.Archives of dermatological research · 2017Pooled it
- UVA irradiation of human skin vasodilates arterial vasculature and lowers blood pressure independently of nitric oxide synthase.The Journal of investigative dermatology · 2014Trial
- Antihypertensive Medication as a Risk Factor For Basal Cell Carcinoma: A Nationwide Registry-based Case-control Study.Acta dermato-venereologica · 2025Article
- Brighter nights and darker days predict higher mortality risk: A prospective analysis of personal light exposure in >88,000 individuals.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Article
- UVA and Seasonal Patterning of 56 370 Myocardial Infarctions Across Scotland, 2000-2011.Journal of the American Heart Association · 2019Article
- The effects of two different doses of ultraviolet-A light exposure on nitric oxide metabolites and cardiorespiratory outcomes.European journal of applied physiology · 2018Article
- Ultraviolet Radiation-Induced Production of Nitric Oxide:A multi-cell and multi-donor analysis.Scientific reports · 2017Article
- The association between osteoporotic hip fractures and actinic lesions as a biomarker for cumulative sun exposure in older people-a retrospective case-control study in Argentina.Journal of bone and mineral metabolism · 2017Article
- Skin Cancer: Epidemiology, Disease Burden, Pathophysiology, Diagnosis, and Therapeutic Approaches.Dermatology and therapy · 2017Review
- Cutaneous control of blood pressure.Current opinion in nephrology and hypertension · 2016Review
- Immortal person-time bias in the association between herpes zoster and survival following autologous stem cell transplantation.Bone marrow transplantation · 2015Article
- Time at risk and intention-to-treat analyses: parallels and implications for inference.Epidemiology (Cambridge, Mass.) · 2015Article
- Avoiding blunders involving 'immortal time'.International journal of epidemiology · 2014Article
- Ultraviolet radiation and its effects on pregnancy: A review study.Journal of family medicine and primary careReview
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSun exposure is the single most important risk factor for skin cancer, but sun exposure may also have beneficial effects on health. We tested the hypothesis that individuals with skin cancer (non-melanoma skin cancer and cutaneous malignant melanoma) have less myocardial infarction, hip fracture and death from any cause, compared with general population controls.
methodsWe examined the entire Danish population above age 40 years from 1980 through 2006, comprising 4.4 million individuals. Diagnoses of non-melanoma skin cancer (n=129,206), cutaneous malignant melanoma (n=22,107), myocardial infarction (n=327,856), hip fracture (n=129,419), and deaths from any cause (n=1,629,519) were drawn from national registries.
resultsIn individuals with vs without non-melanoma skin cancer, multifactorially adjusted odds ratios were 0.96 (95% confidence interval: 0.94-0.98) for myocardial infarction and 1.15 (1.12-1.18) for hip fracture, and the multifactorially adjusted hazard ratio was 0.52 (0.52-0.53) for death from any cause. Risk of hip fracture was reduced (odds ratios were below 1.0) in individuals below age 90 years. In individuals with vs without cutaneous malignant melanoma, corresponding odds ratios were 0.79 (0.74-0.84) for myocardial infarction and 0.84 (0.76-0.93) for hip fracture, and the corresponding hazard ratio for death from any cause was 0.89 (0.87-0.91); however, cutaneous malignant melanoma was associated positively with death from any cause in some individuals.
conclusionsIn this nationwide study, having a diagnosis of skin cancer was associated with less myocardial infarction, less hip fracture in those below age 90 years and less death from any cause. Causal conclusions cannot be made from our data. A beneficial effect of sun exposure per se needs to be examined in other studies.
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