Evidence map›Paper›PMID 24038340›Full record

ArticleJournal of cellular biochemistry2014

Catabolism of host-derived compounds during extracellular bacterial infections.

Jamie A Meadows, Matthew J Wargo

Abstract read
In one paragraph

Article in Journal of cellular biochemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jamie A MeadowsDepartment of Microbiology and Molecular Genetics, University of Vermont College of Medicine, Burlington, Vermont, 05405.
Matthew J Wargo

Funding

VERMONT IMMUNOBIOLOIGY/ INFECTIOUS DISEASES CENTERP20RR021905 · NCRR · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI MATRAJT, MARIANA L · 2006 to 2011
$14.5M
Vermont Immunobioloigy/ Infectious Diseases CenterP20GM103496 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI BUDD, RALPH C · 2012 to 2015
$8.7M
Vermont Immunology/Infectious Diseases Training GrantT32AI055402 · NIAID · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI GARY E WARD · 2005 to 2026
$2.7M
Pseudomonas detection and metabolism of sphingosineR01AI103003 · NIAID · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI WARGO, MATTHEW J · 2013 to 2017
$1.4M
NCRR NIH HHS P20 RR021905NIAID NIH HHS R01 AI103003NIAID NIH HHS R01AI103003NIAID NIH HHS T32 AI055402NIGMS NIH HHS P20 GM103496NIGMS NIH HHS P20 GM103496‐07
6 · The paper itself

Abstract

Efficient catabolism of host-derived compounds is essential for bacterial survival and virulence. While these links in intracellular bacteria are well studied, such studies in extracellular bacteria lag behind, mostly for technical reasons. The field has identified important metabolic pathways, but the mechanisms by which they impact infection and in particular, establishing the importance of a compound's catabolism versus alternate metabolic roles has been difficult. In this review we will examine evidence for catabolism during extracellular bacterial infections in animals and known or potential roles in virulence. In the process, we point out key gaps in the field that will require new or newly adapted techniques.

Indexed as

MetabolismAmino AcidsAnimalsBacteriaBacterial InfectionsCarbohydrate MetabolismHost-Pathogen InteractionsAmino AcidsCATABOLISMINFECTIONPHYSIOLOGY

Identifiers

PMID24038340
PMCPMC4088938

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.