ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2014
The effect of low- and high-velocity tendon excursion on the mechanical properties of human cadaver subsynovial connective tissue.
Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 24 citations in OpenAlex.
- The Median Nerve Displays Adaptive Characteristics When Exposed to Repeated Pinch Grip Efforts of Varying Rates of Force Development: An Ultrasonic Investigation.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025Article
- Relative Motion of the Connective Tissue in Carpal Tunnel Syndrome: The Relation with Disease Severity and Clinical Outcome.Ultrasound in medicine & biology · 2020Article
- Median Nerve Transverse Mobility and Outcome after Carpal Tunnel Release.Ultrasound in medicine & biology · 2019Article
- The biomechanics of subsynovial connective tissue in health and its role in carpal tunnel syndrome.Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2018Review
- Ultrasound-guided hydrodissection decreases gliding resistance of the median nerve within the carpal tunnel.Muscle & nerve · 2018Article
- Delineation of the mechanisms of tendon gliding resistance within the carpal tunnel.Clinical biomechanics (Bristol, Avon) · 2017Article
- Development of a hyperelastic material model of subsynovial connective tissue using finite element modeling.Journal of biomechanics · 2016Article
- The effect of tendon excursion velocity on longitudinal median nerve displacement: differences between carpal tunnel syndrome patients and controls.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2015Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 2 countries.
Funding
Abstract
Fibrosis of the subsynovial connective tissue (SSCT) in the carpal tunnel is the most common histological finding in carpal tunnel syndrome (CTS). Fibrosis may result from damaged SSCT. Previous studies found that with low-velocity (2 mm/s), tendon excursions can irreversibly damage the SSCT. We investigated the effect of tendon excursion velocity in the generation of SSCT damage. Nine human cadaver wrists were used. Three repeated cycles of ramp-stretch testing were performed simulating 40%, 60%, 90%, and 120% of the middle finger flexor tendon superficialis physiological excursion with an excursion velocity of 60 mm/s. Energy and force were calculated and normalized by values obtained in the first cycle for each excursion level. Data were compared with low-velocity excursion data. For high-velocity excursions, a significant drop in the excursion energy ratio was first observed at an excursion level of 60% physiological excursion (p < 0.024) and that for low-velocity excursions was first observed at 90% physiological excursion (p < 0.038). Furthermore, the energy ratio was lower at 60% for high velocities (p ≤ 0.039). Increasing velocity lowers the SSCT damage threshold. This finding may be relevant for understanding the pathogenesis of SSCT fibrosis, such as that accompanying CTS, and a relationship with occupational factors.
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