Evidence map›Paper›PMID 24037911›Full record

ArticleHepatology (Baltimore, Md.)2014

Isoniazid hepatotoxicity: progress in understanding the immunologic component.

Laura James, Dean Roberts

Abstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Hepatology (Baltimore, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Laura JamesDepartment of Pediatrics, University of Arkansas for Medical Sciences, Section of Clinical Pharmacology and Toxicology, Arkansas Children's Hospita, Little Rock, AR.
Dean Roberts

Funding

Adduct Dipstick for Diagnosis of Acetaminophen ToxicityR42DK079387 · NIDDK · ACETAMINOPHEN TOXICITY DIAGNOSTICS, LLC · PI JAMES, LAURA PHILLIPS · 2011 to 2018
$4.4M
AcetaSTAT Validation and CommercializationSB1DK079387 · NIDDK · ACETAMINOPHEN TOXICITY DIAGNOSTICS, LLC · PI JAMES, LAURA P · 2022 to 2025
$3.5M
Identification of new mechanistic biomarkers of adverse responses to acetaminopheR01DK081406 · NIDDK · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI JAMES, LAURA P · 2009 to 2013
$1.9M
Dipstick Assay for Detection of Acetaminophen Protein AdductsR41DK079387 · NIDDK · ACETAMINOPHEN TOXICITY DIAGNOSTICS, LLC · PI JAMES, LAURA P · 2008 to 2010
$489k
NIDDK NIH HHS DK079387NIDDK NIH HHS DK081406NIDDK NIH HHS R01 DK081406NIDDK NIH HHS R41 DK079387NIDDK NIH HHS R42 DK079387NIDDK NIH HHS SB1 DK079387
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Aryl Hydrocarbon HydroxylasesAutoantibodiesChemical and Drug Induced Liver InjuryCytochrome P-450 CYP2C9Cytochrome P-450 CYP2E1Cytochrome P-450 CYP3AFemaleHumansIsoniazidMaleAryl Hydrocarbon HydroxylasesAutoantibodiesCYP2C9 protein, humanCYP3A4 protein, humanCytochrome P-450 CYP2C9Cytochrome P-450 CYP2E1Cytochrome P-450 CYP3AIsoniazid

Identifiers

PMID24037911
PMCPMC4125002

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.