Evidence map›Paper›PMID 24037788›Full record

ReviewCancer2013

Integration of cancer genomics with treatment selection: from the genome to predictive biomarkers.

Thomas J Ow, Vlad C Sandulache, Heath D Skinner, Jeffrey N Myers

Abstract readReview
In one paragraph

Review in Cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Comparative Effectiveness of Biomarkers to Target Cancer Treatment: Modeling Implications for Survival and Costs.Medical decision making : an international journal of the Society for Medical Decision Making · 2016
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas J OwDepartment of Otorhinolaryngology-Head and Neck Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York; Department of Pathology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York.
Vlad C Sandulache
Heath D Skinner
Jeffrey N Myers

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Carlos del Rio · 2002 to 2026
$74.0M
Comprehensive Analysis of Genetic Alterations in Oral CancerRC2DE020958 · NIDCR · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI GIBBS, RICHARD A, MYERS, JEFFREY NICHOLAS · 2009 to 2010
$2.4M
NIAID NIH HHS P30 AI050409NIDCR NIH HHS RC2 DE020958
6 · The paper itself

Abstract

The field of cancer genomics is rapidly advancing as new technology provides detailed genetic and epigenetic profiling of human cancers. The amount of new data available describing the genetic make-up of tumors is paralleled by rapid advances in drug discovery and molecular therapy currently under investigation to treat these diseases. This review summarizes the challenges and approaches associated with the integration of genomic data into the development of new biomarkers in the management of cancer.

Indexed as

Biomarkers, TumorGenomicsHumansMolecular Targeted TherapyNeoplasmsBiomarkers, Tumorbiologic markersclinical trials as topiccomputational biologygenomicsmolecular targeted therapyneoplasmssystems biologytherapeutics

Identifiers

PMID24037788
PMCPMC3930628

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.