ReviewHead and neck pathology2014
Calcifying epithelial odontogenic tumour with clear langerhans cells: a novel variant, report of a case and review of the literature.
Review in Head and neck pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Malignant transformation of calcifying epithelial odontogenic tumour: A systematic review.Journal of clinical and experimental dentistry · 2025Review
- BRAF p.V600E-Negative Langerhans Cell Histiocytosis Associated with a Periapical Cyst: A Case Presentation with Broad Review of the Differential Diagnosis and Disease Pathophysiology.Head and neck pathology · 2025Review
- Sclerosing Odontogenic Carcinoma: A Unique Odontogenic Carcinoma with Metastatic Potential.Head and neck pathology · 2025Review
- Non-Calcifying/Langerhans Cell-Rich Calcifying Epithelial Odontogenic Tumour: A Critical Review of the Rare and Distinctive Entity.Head and neck pathology · 2023Review
- CEOT Variants or Entities: Time for a Rethink? A Case Series with Review of the Literature.Head and neck pathology · 2021Review
- Hybrid odontogenic tumor masquerading as a salivary gland lesion: A diagnostic predicament.Journal of oral and maxillofacial pathology : JOMFP · 2021Article
- Non-calcifying Langerhans Cell Rich Variant of Calcifying Epithelial Odontogenic Tumor and Amyloid Rich Variant of Central Odontogenic Fibroma: A Unique Entity or a Spectrum?Frontiers in oral health · 2021Review
- What Is the Non-calcifying Langerhans Cell-Rich Variant of Calcifying Epithelial Odontogenic Tumor?Head and neck pathology · 2019Article
- Microcystic Calcifying Epithelial Odontogenic Tumor.Head and neck pathology · 2018Article
- Is Conservative Surgery the Best Approach for Peripheral Calcifying Epithelial Odontogenic Tumors?The open dentistry journal · 2018Review
- Non-calcifying and Langerhans cell-rich variant of calcifying epithelial odontogenic tumor.Journal of dental sciences · 2016Review
- Peripheral Calcifying Epithelial Odontogenic Tumour Mimicking a Gingival Inflammation: A Diagnostic Dilemma.Case reports in dentistry · 2016Article
- Clear cell variant of calcifying epithelial odontogenic tumor: Case report with immunohistochemical findings.Journal of clinical and experimental dentistry · 2015Article
- Noncalcifying clear-cell variant of calcifying epithelial odontogenic tumor: A case report and review.Journal of oral and maxillofacial pathology : JOMFPArticle
- Odontogenic tumors: A review of 93 cases in the Vidharba region of Maharashtra.Journal of oral and maxillofacial pathology : JOMFPArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clear cell calcifying epithelial odontogenic tumour (CCEOT) is a rare variant of calcifying epithelial odontogenic tumor (CEOT). While it is not surprising to find clear cells in odontogenic lesions, the exact nature of the clear cells in CCEOT has not been elucidated. Herein, we report a case of peripheral CCEOT of anterior mandible in a 37 year old black female. Histologically, the tumour consisted of cords and small nests of clear cells surrounded by dense deposits of amyloid and basophilic calcifications. The cells possessed abundant clear cytoplasm and eccentrically located indented nuclei. Admixed with the clear cells were eosinophilic cuboidal to polyhedral cells. The clear cells were PAS negative and immunoreactive for S100 protein, CD1a and Langerin. The clear cells were negative for MNF-116, SMA, Desmin and CK-19. It is therefore recommended to recognize two variants of CCEOT, namely, CEOT with clear cell change and CEOT with clear Langerhans cells (LC). We further suggest that the contradictory term "non-calcifying variant of calcifying epithelial odontogenic tumour with LC" to be abandoned, as the current case clearly indicates that LC could be seen in CEOT irrespective of the presence or absence of calcifications.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.