ArticleInternational ophthalmology2014
Measurements of elastic modulus for human anterior lens capsule with atomic force microscopy: the effect of loading force.
Article in International ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Regional Differences in Young's Modulus of the Porcine Lens Capsule.Annals of biomedical engineering · 2026Article
- Micromorphology analysis of the anterior human lens capsule.Molecular vision · 2018Article
- Optical coherence elastography in ophthalmology.Journal of biomedical optics · 2017Review
- Lens capsule structure assessed with atomic force microscopy.Molecular vision · 2015Article
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of the study was to appraise the effect of loading force magnitude on the determination of the elastic modulus of the anterior lens capsule through atomic force microscopy. Four human anterior lens capsules taken during phacoemulsification cataract surgery were studied, free of epithelial cells, with atomic force microscopy. For the experiment, five different indentation loading forces were applied to near areas of the specimen. Experimental data was exported and analyzed according to the Hertz model to obtain the Young's modulus with regards to the elastic behavior of the material. Force-distance curves were acquired by applying a load of 2, 5, 10, 20 and 30 nN. When examining the results it was evident that determination of Young's modulus of the anterior lens capsule is dependent on the loading force concerning the examined range. Loading forces of 10 and 20 nN led to results without significant difference (p > 0.05) and more reproducible (coefficients of variation 12.4 and 11.7 %, respectively).
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