ReviewCurrent atherosclerosis reports2013
Lipids and the endothelium: bidirectional interactions.
Review in Current atherosclerosis reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 56 citations in OpenAlex.
- High Serum Monounsaturated Fatty Acids Levels May Increase Risk of Cardiovascular Disease: A Mendelian Randomization Study.Iranian journal of medical sciences · 2026Article
- Systems genomics reveals age- and sex-dependent metabolic dysregulation fromPhysiological genomics · 2026Article
- Metabolic Symbiosis Between Cancer Cells and Endothelial Cells: A Key Driver of Tumor Angiogenesis.Advances in experimental medicine and biology · 2026Review
- Remnant Cholesterol is Associated with Blood Pressure Control in US Adults with Hypertension: NHANES 2007-2018 Analysis.Vascular health and risk management · 2025Article
- Two Sides of Triglycerides in Atherogenesis: An Essential Contributor.Clinical Medicine Insights. Cardiology · 2025Review
- Metabolic Responses to Redox Stress in Vascular Cells.Antioxidants & redox signaling · 2024Review
- Cellular metabolism changes in atherosclerosis and the impact of comorbidities.Frontiers in cell and developmental biology · 2024Review
- Suppression of angiopoietin-like 4 reprograms endothelial cell metabolism and inhibits angiogenesis.Nature communications · 2023Article
- Transcriptome analysis highlights the role of ferroptosis in palmitic acid-induced endothelial dysfunction.Sexual medicine · 2023Article
- Modulation of endothelium function by fatty acids.Molecular and cellular biochemistry · 2022Review
- Severe Hypertriglyceridemia as a Cause of Aortic Thrombus with Peripheral Embolic Complications.Kansas journal of medicine · 2022Article
- Identification of Endothelial Proteins in Plasma Associated With Cardiovascular Risk Factors.Arteriosclerosis, thrombosis, and vascular biology · 2021Article
- Formation and Cellular Impact of Cholesterol Crystals in Health and Disease.Advanced biology · 2021Review
- Diabetes Mellitus and Its Metabolic Complications: The Role of Adipose Tissues.International journal of molecular sciences · 2021Review
- Eruptive xanthoma model reveals endothelial cells internalize and metabolize chylomicrons, leading to extravascular triglyceride accumulation.The Journal of clinical investigation · 2021Article
- Endothelial cell and T-cell crosstalk: Targeting metabolism as a therapeutic approach in chronic inflammation.British journal of pharmacology · 2021Review
- Secondary Metabolites of Plants as Modulators of Endothelium Functions.International journal of molecular sciences · 2021Review
- Article
- Angiogenesis in Adipose Tissue: The Interplay Between Adipose and Endothelial Cells.Frontiers in physiology · 2020Review
- Tipping the scales: Are females more at risk for obesity- and high-fat diet-induced hypertension and vascular dysfunction?British journal of pharmacology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 3 countries.
Funding
Abstract
The endothelium is often viewed solely as the barrier that prevents the penetration of circulating lipoproteins into the arterial wall. However, recent research has demonstrated that the endothelium has an important part in regulating circulating fatty acids and lipoproteins, and is in turn affected by these lipids/lipoproteins in ways that appear to have important repercussions for atherosclerosis. Thus, a number of potentially toxic lipids are produced during lipolysis of lipoproteins at the endothelial cell surface. Catabolism of triglyceride-rich lipoproteins creates free fatty acids that are readily taken up by endothelial cells, and, likely through the action of acyl-CoA synthetases, exacerbate inflammatory processes. In this article, we review how the endothelium participates in lipoprotein metabolism, how lipids alter endothelial functions, and how lipids are internalized, processed, and transported into the subendothelial space. Finally, we address the many endothelial changes that might promote atherogenesis, especially in the setting of diabetes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.