Evidence map›Paper›PMID 24037085›Full record

ArticlePediatric radiology2014

Renal sonography with Doppler for detecting suspected pediatric renin-mediated hypertension - is it adequate?

Patricia K Castelli, Jonathan R Dillman, David B Kershaw, Shokoufeh Khalatbari, James C Stanley, Ethan A Smith

Abstract read
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In one paragraph

Article in Pediatric radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Approach to pediatric renovascular hypertension.Childhood kidney diseases · 2025
    Review
  4. Pediatric Renovascular Hypertension: Diagnosis and Management.Seminars in interventional radiology · 2025
    Review
  5. Review
  6. Article
  7. Pediatric Hypertension: A Condition That Matters.Children (Basel, Switzerland) · 2024
    Review
  8. Review
  9. Review
  10. Pediatric hypertension: an updated review.Clinical hypertension · 2020
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Patricia K CastelliDepartment of Radiology, C. S. Mott Children's Hospital, Section of Pediatric Radiology, University of Michigan Health System, 1540 E. Hospital Drive, Ann Arbor, MI, 48109, USA.
Jonathan R Dillman
David B Kershaw
Shokoufeh Khalatbari
James C Stanley
Ethan A Smith
Michigan Medicine · USUniversity Health System · USC. S. Mott Children's Hospital · USUniversity of Michigan–Ann Arbor · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRenal Doppler US is used to evaluate suspected vascular causes of hypertension in children, despite mostly unknown diagnostic performance characteristics.

objectiveTo evaluate renal Doppler US for detecting vascular causes of hypertension in children with high clinical suspicion of aortic or renal artery narrowing. MATERIALS AND

methodsWe identified pediatric renal Doppler US examinations performed for hypertension between January 1995 and June 2010 at our institution. We excluded children without follow-up angiography (CT-, MR-, or catheter-based). Two pediatric radiologists reviewed imaging studies and documented relevant findings. Intrarenal spectral Doppler resistive index measurement <0.5 or tardus parvus waveform constituted a positive examination.

resultsThirty-five boys and 13 girls underwent renal Doppler US and confirmatory imaging (mean age  =  9.0 years). Nineteen US examinations were truly negative, two were falsely negative, 18 were truly positive (16 involved narrowing of the aorta or main renal artery) and nine were falsely positive. Sonography had a sensitivity and specificity of 90% and 68%, respectively, for detecting a vascular cause of hypertension.

conclusionRenal Doppler sonography reliably detects renin-mediated hypertension caused by aortic or main renal artery narrowing in children. More studies are needed to determine its ability to detect intrarenal and accessory renal artery stenoses.

Indexed as

AdolescentChildChild, PreschoolFalse Negative ReactionsFalse Positive ReactionsFemaleHumansHypertension, RenovascularImage Interpretation, Computer-AssistedInfantKidneyMaleObserver VariationReproducibility of ResultsSensitivity and SpecificityUltrasonography, Doppler

Identifiers

PMID24037085
OpenAlexW2005332840

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.