Evidence map›Paper›PMID 24036688›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2014

Serum 25-hydroxyvitamin D predicts severity in Parkinson's disease patients.

Ying Liu, Ben-Shu Zhang

Abstract read
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In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. No Vitamin D Deficiency in Patients with Parkinson's Disease.Degenerative neurological and neuromuscular disease · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Benefits of Vitamins in the Treatment of Parkinson's Disease.Oxidative medicine and cellular longevity · 2019
    Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ying LiuDepartment of Neurology, General Hospital, Tianjin Medical University, No. 154, Anshandao Heping District, Tianjin, 300052, People's Republic of China.
Ben-Shu Zhang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, increasing evidence has shown that individuals with Parkinson's disease (PD) have lower levels of 25-hydroxyvitamin D [25(OH) D] relative to healthy controls. We therefore evaluated the relationship between serum 25(OH) D levels and severity in Chinese patients with a Parkinson's disease. From July 2010 to June 2012, consecutive PD patients admitted to the Department of Neurology of General Hospital, Tianjin Medical University, were identified. Clinical information and disease duration were collected. Serum level of 25(OH) D was measured at baseline. PD severity was assessed at admission using the Hoehn and Yahr (HY) stage and Unified Parkinson's Disease Rating Stage (UPDRS) total score. The results indicated that the mean serum 25(OH) D levels were significantly lower in PD patients as compared to normal cases (P < 0.001). There was a negative correlation between levels of 25(OH) D and the disease duration [r (spearman) = -0.124, P = 0.041]. There was a significant negative relationship between circulating serum 25(OH) D levels and severity of Parkinson's disease evaluated by HY stage (P = 0.030) and UPDRS Stage (P = 0.000) even after multivariate adjustment for possible confounders: age, gender, disease duration, levels of Ca, ALP, blood glucose, and seasons. These results suggest that lower 25(OH) D levels may be associated with severity of PD in Chinese patients.

Indexed as

AgedAged, 80 and overAsian PeopleCohort StudiesFemaleHumansMaleMiddle AgedParkinson DiseaseSeverity of Illness IndexVitamin D25-hydroxyvitamin DVitamin D

Identifiers

PMID24036688

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.