Evidence map›Paper›PMID 24036004›Full record

ArticleJournal of biomedical informatics2013

Unsupervised mining of frequent tags for clinical eligibility text indexing.

Riccardo Miotto, Chunhua Weng

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. IDENTIFICATION OF QUESTIONABLE EXCLUSION CRITERIA IN MENTAL DISORDER CLINICAL TRIALS USING A MEDICAL ENCYCLOPEDIA.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2016
    Article
  8. How Have Cancer Clinical Trial Eligibility Criteria Evolved Over Time?AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2016
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Trend and Network Analysis of Common Eligibility Features for Cancer Trials in ClinicalTrials.gov.Smart health : international conference, ICSH ... ICSH (Conference : Smart Health) · 2014
    Article
  15. A method for analyzing commonalities in clinical trial target populations.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2014
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Riccardo MiottoDepartment of Biomedical Informatics, Columbia University, New York, NY 10032, USA.
Chunhua Weng

Funding

Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Bridging the Semantic Gap Between Research Eligibility Criteria and Clinical DataR01LM009886 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WENG, CHUNHUA · 2009 to 2020
$5.3M
Developing Flexible EHR Plug-ins to Re-Engineer Clinical Care and Research WorkflowsR01LM010815 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HOMMA, SHUNICHI, WENG, CHUNHUA · 2010 to 2013
$1.9M
NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1TR000040NLM NIH HHS R01 LM009886NLM NIH HHS R01LM009886NLM NIH HHS R01 LM010815
6 · The paper itself

Abstract

Clinical text, such as clinical trial eligibility criteria, is largely underused in state-of-the-art medical search engines due to difficulties of accurate parsing. This paper proposes a novel methodology to derive a semantic index for clinical eligibility documents based on a controlled vocabulary of frequent tags, which are automatically mined from the text. We applied this method to eligibility criteria on ClinicalTrials.gov and report that frequent tags (1) define an effective and efficient index of clinical trials and (2) are unlikely to grow radically when the repository increases. We proposed to apply the semantic index to filter clinical trial search results and we concluded that frequent tags reduce the result space more efficiently than an uncontrolled set of UMLS concepts. Overall, unsupervised mining of frequent tags from clinical text leads to an effective semantic index for the clinical eligibility documents and promotes their computational reuse.

Indexed as

Clinical Trials as TopicData MiningEligibility DeterminationHumansClinical trialsControlled vocabularyEligibility criteriaInformation filteringInformation storage and retrievalTags

Identifiers

PMID24036004
PMCPMC3843986

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.