Evidence map›Paper›PMID 24034708›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2013

Prominent impact of community risk factors on kidney transplant candidate processes and outcomes.

J D Schold, E L G Heaphy, L D Buccini, E D Poggio, T R Srinivas, D A Goldfarb, S M Flechner, J R Rodrigue, J D Thornton, A R Sehgal

Abstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Neighborhood-level social determinants of health measures independently predict receipt of living donor liver transplantation in the United States.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Deceased donor kidneys from higher distressed communities are significantly less likely to be utilized for transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Neighborhood socioeconomic deprivation is associated with worse patient and graft survival following pediatric liver transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020
    Article
  15. Modest rates and wide variation in timely access to repeat kidney transplantation in the United States.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020
    Article
  16. Article
  17. Excluding patients from transplant due to social support: Results from a national survey of transplant providers.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2019
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

J D ScholdDepartment of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH; Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH; Center for Health Disparities, MetroHealth Medical Center and Case Western Reserve University, Cleveland, OH.
E L G Heaphy
L D Buccini
E D Poggio
T R Srinivas
D A Goldfarb
S M Flechner
J R Rodrigue
J D Thornton
A R Sehgal

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024989 · NCRR · CASE WESTERN RESERVE UNIVERSITY · PI DAVIS, PAMELA B · 2007 to 2011
$53.7M
Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
Transplant navigator interventuon to overcome barriers to kidney transplantionP60MD002265 · NIMHD · CASE WESTERN RESERVE UNIVERSITY · PI SEHGAL, ASHWINI · 2007 to 2016
$10.5M
Kidney Donor Outcomes Cohort (KDOC) StudyR01DK085185 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI MANDELBROT, DIDIER A, RODRIGUE, JAMES R · 2011 to 2014
$2.8M
NCATS NIH HHS UL1 TR000439NCRR NIH HHS RR024989NCRR NIH HHS UL1 RR024989NIDDK NIH HHS R01 DK085185NIDDK NIH HHS R01DK085185NIMHD NIH HHS P60 MD002265NIMHD NIH HHS P60MD00265
6 · The paper itself

Abstract

Numerous factors impact patients' health beyond traditional clinical characteristics. We evaluated the association of risk factors in kidney transplant patients' communities with outcomes prior to transplantation. The primary exposure variable was a community risk score (range 0-40) derived from multiple databases and defined by factors including prevalence of comorbidities, access and quality of healthcare, self-reported physical and mental health and socioeconomic status for each U.S. county. We merged data with the Scientific Registry of Transplant Recipients (SRTR) and utilized risk-adjusted models to evaluate effects of community risk for adult candidates listed 2004-2010 (n = 209 198). Patients in highest risk communities were associated with increased mortality (adjusted hazard ratio [AHR] = 1.22, 1.16-1.28), decreased likelihood of living donor transplantation (adjusted odds ratio [AOR] = 0.90, 0.85-0.94), increased waitlist removal for health deterioration (AHR = 1.36, 1.22-1.51), decreased likelihood of preemptive listing (AOR = 0.85, 0.81-0.88), increased likelihood of inactive listing (AOR = 1.49, 1.43-1.55) and increased likelihood of listing for expanded criteria donor kidneys (AHR = 1.19, 1.15-1.24). Associations persisted with adjustment for rural-urban location; furthermore the independent effects of rural-urban location were largely eliminated with adjustment for community risk. Average community risk varied widely by region and transplant center (median = 21, range 5-37). Community risks are powerful factors associated with processes of care and outcomes for transplant candidates and may be important considerations for developing effective interventions and measuring quality of care of transplant centers.

Indexed as

AdultAgedCommunity Health ServicesFemaleHealth Services AccessibilityHumansKidney Failure, ChronicKidney TransplantationLiving DonorsMaleMiddle AgedOdds RatioRisk FactorsRural PopulationTissue DonorsTreatment OutcomeAccess to transplantationcomorbiditykidney transplantationliving donor transplantationpreemptiverisk factorssocioeconomic statuswaiting listwaitlist mortality

Identifiers

PMID24034708
PMCPMC3775281

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.