ArticleJournal of clinical hypertension (Greenwich, Conn.)2013
Hypertension in pregnancy is a risk factor for microalbuminuria later in life.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- A systematic review on the determinants of long-term kidney sequelae after hypertensive diseases of pregnancy.Acta obstetricia et gynecologica Scandinavica · 2025Pooled it
- Proteinuria in Preeclampsia and Long-Term Risk of Maternal Kidney and Cardiovascular Disease: A Population-Based Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2026Article
- Hypoalbuminemia as a severity predictor of preeclampsia in a multicenter study from Indonesia.Scientific reports · 2026Article
- Maternal Microvascular Dysfunction During and After Preeclamptic Pregnancy.Comprehensive Physiology · 2024Review
- Review
- Article
- VASCULAR AND RENAL MECHANISMS OF PREECLAMPSIA.Current opinion in physiology · 2023Article
- Article
- Hypertensive Diseases in Pregnancy and Kidney Function Later in Life: The Genetic Epidemiology Network of Arteriopathy (GENOA) Study.Mayo Clinic proceedings · 2022Article
- Preeclampsia and Kidney Disease: Deciphering Cause and Effect.Current hypertension reports · 2020Review
- Preeclampsia: Novel Mechanisms and Potential Therapeutic Approaches.Frontiers in physiology · 2018Review
- Spot urine protein measurements in normotensive pregnancies, pregnancies with isolated proteinuria and preeclampsia.American journal of physiology. Regulatory, integrative and comparative physiology · 2017Article
- Preeclampsia and ESRD: The Role of Shared Risk Factors.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2017Article
- Hypertensive pregnancy disorders and future renal disease.Current hypertension reports · 2014Review
- How does preeclampsia predispose to future cardiovascular disease?Current hypertension reports · 2014Review
- Advances in the pathophysiology of pre-eclampsia and related podocyte injury.Kidney international · 2014Review
- Pre-eclampsia and cardiovascular disease.Cardiovascular research · 2014Review
- Persistent urinary podocyte loss following preeclampsia may reflect subclinical renal injury.PloS one · 2014Article
- Microalbuminuria and hypertension in pregnancy: role of aldosterone and inflammation.Journal of clinical hypertension (Greenwich, Conn.) · 2013Article
- Long term follow up of biomarkers of podocyte damage and renal function in patients with and without preeclampsia.Jornal brasileiro de nefrologiaObservational
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
Abstract
The authors aimed to compare renal function by estimated glomerular filtration rate and albuminuria in 3 groups of women: nulliparous women, women with a history of normotensive pregnancies, and women with a history of at least one hypertensive pregnancy. Women who participated in the second Family Blood Pressure Program Study visit (2000-2004) and had serum creatinine and urine albumin measurements (n=3015) were categorized as having had no pregnancy lasting >6 months (n=341), having had only normotensive pregnancies (n=2199), or having had at least 1 pregnancy with hypertension (n=475) based on a standardized questionnaire. Women who reported having had at least one pregnancy with hypertension were significantly more likely to be hypertensive (75.6% vs 59.4%, P<.001), diabetic (34.2% vs 27.3%, P≤.001), and have higher body mass index (32.8 vs 30.5, P<.001) than those who reported normotensive pregnancies. There was a significantly greater risk of microalbuminuria (urine albumin-creatinine ratio >25 mg/g) in those who reported at least one pregnancy with hypertension (odds ratio, 1.37; confidence interval, 1.02-1.85; P=.04) than in those with normotensive pregnancies, after adjusting for risk factors for chronic kidney and cardiovascular disease. Hypertension in pregnancy is associated with an increased risk of future microalbuminuria.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.