Evidence map›Paper›PMID 24034613›Full record

ReviewCell host & microbe2013

What pathogens have taught us about posttranslational modifications.

Dor Salomon, Kim Orth

Open access · bronzeAbstract readReview
In one paragraph

Review in Cell host & microbe, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Impact of Lysine Succinylation on the Biology of Fungi.Current issues in molecular biology · 2024
    Review
  11. Article
  12. A secreted sirtuin fromScience advances · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. eLife · 2022
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Dor SalomonDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.
Kim Orth
The University of Texas Southwestern Medical Center · US

Funding

Analysis of an orchestrated cell death mediated by Vibrio parahaemolytics T3SS1R01AI087808 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI ORTH, KIM · 2010 to 2014
$1.9M
Analysis of newly identified adhesin used by pathogenic Gram-negative bacteriaR21AI096133 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI ORTH, KIM · 2012 to 2013
$423k
NIAID NIH HHS R01 AI087808NIAID NIH HHS R01-AI087808NIAID NIH HHS R21 AI096133NIAID NIH HHS R21-AI096133
6 · The paper itself

Abstract

Pathogens use various mechanisms to manipulate host processes to promote infection. Decades of research on pathogens have revealed not only the molecular mechanisms that these microbes use to replicate and survive within host cells, but also seminal information on how host signaling machinery regulates cellular processes. Among these discoveries are mechanisms involving posttranslational modifications that alter the activity, localization, or interactions of the modified protein. Herein, we examine how pathogens have contributed to our basic understanding of three posttranslational modifications: phosphorylation, NMPylation, and ubiquitylation. Over the years, technologies, techniques and research tools have developed side by side with the study of pathogens, facilitating the discovery of protein modifications and furthering our understanding of how they contribute to both infection and cellular functions.

Indexed as

Host-Pathogen InteractionsProtein Processing, Post-TranslationalSignal TransductionBacteriaPhosphorylationProteinsUbiquitinationProteins

Identifiers

PMID24034613
PMCPMC5785091
OpenAlexW2093475793

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.