Evidence map›Paper›PMID 24034553›Full record

ArticleMaternal & child nutrition2015

Age at first introduction to complementary foods is associated with sociodemographic factors in children with increased genetic risk of developing type 1 diabetes.

Carin Andrén Aronsson, Ulla Uusitalo, Kendra Vehik, Jimin Yang, Katherine Silvis, Sandra Hummel, Suvi M Virtanen, Jill M Norris, TEDDY Study Group

Abstract readMulticenter Study
In one paragraph

Article in Maternal & child nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

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  12. Effects of Gluten Intake on Risk of Celiac Disease: A Case-Control Study on a Swedish Birth Cohort.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Carin Andrén AronssonDepartment of Clinical Sciences, Lund University/CRC, Malmö, Sweden.
Ulla UusitaloMorsani College of Medicine, University of South Florida, Pediatrics Epidemiology Center, Tampa, Florida, USA.
Kendra VehikMorsani College of Medicine, University of South Florida, Pediatrics Epidemiology Center, Tampa, Florida, USA.
Jimin YangMorsani College of Medicine, University of South Florida, Pediatrics Epidemiology Center, Tampa, Florida, USA.
Katherine SilvisGeorgia Regents University, Augusta, Georgia, USA.
Sandra HummelInstitute of Diabetes Research, Helmholtz Zentrum München, Klinikum rechts der lsar, Technische Universität, München, Germany.
Suvi M VirtanenNutrition Unit, National Institute for Health and Welfare, Helsinki, Finland.
Jill M NorrisDepartment of Epidemiology, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, USA.
TEDDY Study Group
University of South Florida · USAugusta University · USColorado School of Public Health · USHelmholtz Zentrum München · DELund University · SETampere University Hospital · FI

Funding

Data Coordinating Center (DCC)for the Consortium for Identification of EnvironmenUC4DK095300 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2011 to 2011
$56.0M
Data Coordinating CenterU01DK063790 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2002 to 2006
$50.1M
The Environmental Determinants of Diabetes in Young (TEDDY0U01DK063863 · NIDDK · HOSPITAL DISTRICT OF SOUTHWEST FINLAND · PI TOPPARI, JORMA · 2003 to 2022
$13.5M
The Environmental Triggers of Diabetes (TEDDY) in SwedenU01DK063861 · NIDDK · UNIVERSITY OF WASHINGTON · PI LERNMARK, AKE · 2003 to 2022
$13.4M
THE TEDDY STUDY - COLORADO CLINICAL CENTERU01DK063821 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI REWERS, MARIAN J · 2003 to 2022
$12.3M
The TEDDY Study: Georgia/Florida Clinical CenterU01DK063865 · NIDDK · MEDICAL COLLEGE OF GEORGIA (MCG) · PI MCINDOE, RICHARD A. · 2003 to 2022
$12.3M
The Environmental Determinants of Diabetes in Youth: Washington Clinical CenterU01DK063829 · NIDDK · PACIFIC NORTHWEST RESEARCH INSTITUTE · PI HAGOPIAN, WILLIAM A. · 2003 to 2022
$11.8M
Type 1 Diabetes triggers: diet modification in neonatesU01DK063836 · NIDDK · FORSCHERGRUPPE DIABETES E. V. · PI ZIEGLER, ANETTE · 2003 to 2022
$6.2M
The Environmental Triggers of Diabetes (TEDDY)UC4DK063861 · NIDDK · LUNDS UNIVERSITET · PI LERNMARK, AKE · 2013 to 2013
$5.7M
The Environmental Determinants of Diabetes in the Young (TEDDY) StudyUC4DK063863 · NIDDK · HOSPITAL DISTRICT OF SOUTHWEST FINLAND · PI TOPPARI, JORMA · 2013 to 2013
$5.6M
The TEDDY Study: Georgia/Florida Clinical CenterUC4DK063865 · NIDDK · AUGUSTA UNIVERSITY · PI SHE, JIN-XIONG · 2013 to 2013
$5.3M
The Environmental Determinants of Diabetes in the Young (TEDDY) Colorado ClinicalUC4DK063821 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI REWERS, MARIAN J · 2013 to 2013
$4.9M
NIDDK NIH HHS U01 DK063790NIDDK NIH HHS U01 DK063821NIDDK NIH HHS U01 DK063829NIDDK NIH HHS U01 DK063836NIDDK NIH HHS U01 DK063861NIDDK NIH HHS U01 DK063863NIDDK NIH HHS U01 DK063865NIDDK NIH HHS U01 DK63790NIDDK NIH HHS U01 DK63821NIDDK NIH HHS U01 DK63829NIDDK NIH HHS U01 DK63836NIDDK NIH HHS U01 DK63861NIDDK NIH HHS U01 DK63863NIDDK NIH HHS U01 DK63865NIDDK NIH HHS UC4 DK063821NIDDK NIH HHS UC4 DK063829NIDDK NIH HHS UC4 DK063836NIDDK NIH HHS UC4 DK063861NIDDK NIH HHS UC4 DK063863NIDDK NIH HHS UC4 DK063865NIDDK NIH HHS UC4 DK095300NIDDK NIH HHS UC4 DK63821NIDDK NIH HHS UC4 DK63829NIDDK NIH HHS UC4 DK63836NIDDK NIH HHS UC4 DK63861NIDDK NIH HHS UC4 DK63863NIDDK NIH HHS UC4 DK63865NIDDK NIH HHS UC4 DK95300NLM NIH HHS HHSN267200700014C
6 · The paper itself

Abstract

Infant's age at introduction to certain complementary foods (CF) has in previous studies been associated with islet autoimmunity, which is an early marker for type 1 diabetes (T1D). Various maternal sociodemographic factors have been found to be associated with early introduction to CF. The aims of this study were to describe early infant feeding and identify sociodemographic factors associated with early introduction to CF in a multinational cohort of infants with an increased genetic risk for T1D. The Environmental Determinants of Diabetes in the Young study is a prospective longitudinal birth cohort study. Infants (N = 6404) screened for T1D high risk human leucocyte antigen-DQ genotypes (DR3/4, DR4/4, DR4/8, DR3/3, DR4/4, DR4/1, DR4/13, DR4/9 and DR3/9) were followed for 2 years at six clinical research centres: three in the United States (Colorado, Georgia/Florida, Washington) and three in Europe (Sweden, Finland, Germany). Age at first introduction to any food was reported at clinical visits every third month from the age of 3 months. Maternal sociodemographic data were self-reported through questionnaires. Age at first introduction to CF was primarily associated with country of residence. Root vegetables and fruits were usually the first CF introduced in Finland and Sweden and cereals were usually the first CF introduced in the United States. Between 15% and 20% of the infants were introduced to solid foods before the age of 4 months. Young maternal age (<25 years), low educational level (<12 years) and smoking during pregnancy were significant predictors of early introduction to CF in this cohort. Infants with a relative with T1D were more likely to be introduced to CF later.

Indexed as

Age FactorsGenetic Predisposition to DiseaseInfant Nutritional Physiological PhenomenaSocioeconomic FactorsAdultDiabetes Mellitus, Type 1Edible GrainEuropeFemaleFollow-Up StudiesFruitHLA AntigensHumansInfantLongitudinal StudiesMaleHLA Antigensbreastfeedingcomplementary foodsinfant feedingnewborn feeding behaviourssocioeconomic factorsTEDDY

Identifiers

PMID24034553
PMCPMC4122645
OpenAlexW2136603681

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.