ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2010
Biotechnological production of citric acid.
Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed.
- Eliminating manganese sensitivity and boosting citric acid production in Aspergillus niger through transporters manipulation.Microbial cell factories · 2026Article
- Draft genome assembly of hyper citric acid-producing Aspergillus niger mutant strain developed through gamma radiation bombardment.BMC genomic data · 2026Article
- Industrial Bioreactor Technologies for Modern Biomanufacturing: Recent Applications in Microbial, Mammalian, and Plant-Based Systems.Molecular biotechnology · 2026Review
- Enhanced citric acid production via aconitase co-inhibition strategy using L-cysteine HCl-resistant3 Biotech · 2026Article
- Understanding pellet population heterogeneity of Aspergillus niger in stirred tank and rocking motion bioreactors.Applied microbiology and biotechnology · 2026Article
- From the bench to the reactor: engineered filamentous fungi for biochemical and biomaterial production.Biotechnology for biofuels and bioproducts · 2025Review
- Section-level genome sequencing and comparative genomics ofStudies in mycology · 2025Article
- Cell walls of filamentous fungi - challenges and opportunities for biotechnology.Applied microbiology and biotechnology · 2025Review
- From microbial proteins to cultivated meat for alternative meat-like products: a review on sustainable fermentation approaches.Journal of biological engineering · 2025Article
- Bioleaching of uranium from ores and rocks using filamentous fungi.Frontiers in microbiology · 2025Review
- An overview of key industrial product citric acid production by Aspergillus niger and its application.Journal of industrial microbiology & biotechnology · 2024Review
- Exploring the Impact of Solid-State Fermentation on Fava Bean Flour: A Comparative Study ofFoods (Basel, Switzerland) · 2024Article
- Enhanced Citric Acid Production throughLife (Basel, Switzerland) · 2024Article
- Improving dietary citric acid production by the wild-typeFood science & nutrition · 2024Article
- Citric Acid: Properties, Microbial Production, and Applications in Industries.Molecules (Basel, Switzerland) · 2023Review
- Production of Extracellular Enzymes by Lentinula edodes Strains in Solid-State Fermentation on Lignocellulosic Biomass Sterilized by Physical and Chemical Methods.Current microbiology · 2023Article
- Investigating the Role of Citric Acid as a Natural Acid on the Crystallization of Amoxicillin Trihydrate.ACS omega · 2023Article
- Chemical, Aroma and Pro-Health Characteristics of Kaffir Lime Juice-The Approach Using Optimized HS-SPME-GC-TOFMS, MP-OES, 3D-FL and Physiochemical Analysis.International journal of molecular sciences · 2023Article
- Microbial and Chemical Characterization of Natural-Style Green Table Olives from the Gordal, Hojiblanca and Manzanilla Cultivars.Foods (Basel, Switzerland) · 2023Article
- Citric Acid: A Multifunctional Pharmaceutical Excipient.Pharmaceutics · 2022Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This work provides a review about the biotechnological production of citric acid starting from the physicochemical properties and industrial applications, mainly in the food and pharmaceutical sectors. Several factors affecting citric acid fermentation are discussed, including carbon source, nitrogen and phosphate limitations, pH of culture medium, aeration, trace elements and morphology of the fungus. Special attention is paid to the fundamentals of biochemistry and accumulation of citric acid. Technologies employed at industrial scale such as surface or submerged cultures, mainly employing Aspergillus niger, and processes carried out with Yarrowia lipolytica, as well as the technology for recovering the product are also described. Finally, this review summarizes the use of orange peels and other by-products as feedstocks for the bioproduction of citric acid.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.