ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2009
Antineoplasic activity of Agaricus brasiliensis basidiocarps on different maturation phases.
Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Semisolid culture medium improves mycelial recovery of Agaricus subrufescens cryopreserved in cereal grains.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2019Article
- Structural Properties and Macrophage Activation of Cell Wall Polysaccharides from the Fruiting Bodies ofPolymers · 2018Article
- Photoprotective and Antimutagenic Activity of Agaricus subrufescens Basidiocarp Extracts.Current microbiology · 2015Article
- Mycelial antineoplastic activity of Agaricus blazei.World journal of microbiology & biotechnology · 2014Article
- Agaricus subrufescens: A review.Saudi journal of biological sciences · 2012Article
- Production flush of Agaricus blazei on Brazilian casing layers.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2011Article
- Antioxidant Activity of Agaricus brasiliensis Basidiocarps on Different Maturation Phases.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2011Article
- Long-term cryopreservation of basidiomycetes.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]Review
- Cryopreservation at -75°C of Agaricus subrufescens on wheat grains with sucrose.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]Article
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Authors and funding
7 authors.
Funding
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Abstract
The fungus Agaricus brasiliensis is a Basidiomycete studied because of its immunomodulation and/or antitumor substances. The objective of this study was to verify the Agaricus brasiliensis antineoplasic activity in vivo on different basidiocarp maturation phases on Sarcoma 180 cells implanted in mice. Sarcoma cells were implanted in mice and after seven days mice were divided in three groups. The first group was treated with saline solution, the second group was treated with closed basidiocarp extract solution and the third group was treated with opened basidiocarp extract solution. After 30 days of being daily orally treated with these three solutions all animals suffered euthanasia, and the splenic index, tumor mass and volume were determined. No significant differences of the tumor growth inhibition in function of the different basidiocarp maturation phases for the Agaricus brasiliensis strain were observed. The in vivo basidiocarp antineoplasic average activity was 89.22%.
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