ArticleIranian journal of medical sciences2013
Antibacterial Activity of Thymus Syriacus Boiss Essential Oil and Its Components against Some Syrian Gram-Negative Bacteria Isolates.
Article in Iranian journal of medical sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 25 citations in OpenAlex.
- Antifibrotic Effects ofInternational journal of molecular sciences · 2026Article
- Thymol: properties, synthesis, mechanism of action, and applications.Frontiers in nutrition · 2026Review
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- Exploring the Ecological Preferences and Essential Oil Variability in Wild-Growing Populations of the Endangered Local Greek EndemicPlants (Basel, Switzerland) · 2023Article
- Antibacterial, Antibiofilm, and Antioxidant Activity of 15 Different Plant-Based Natural Compounds in Comparison with Ciprofloxacin and Gentamicin.Antibiotics (Basel, Switzerland) · 2022Article
- Essential Oils fromMolecules (Basel, Switzerland) · 2020Article
- Antimicrobial Activity of Polyphenols and Alkaloids in Middle Eastern Plants.Frontiers in microbiology · 2019Review
- The role of flavor and fragrance chemicals in TRPA1 (transient receptor potential cation channel, member A1) activity associated with allergies.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2015Article
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4 authors at 1 institution in 1 country.
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Abstract
backgroundDespite the medical discoveries of different medicines and advanced ways of treatment, statistics have shown that the number of patients is increasing. This may be due to chemical drugs used in healthcare, agriculture, and diets. This soaring demand in medicines urges us to look for natural sources such as aromatic plants and essential oils, which are rich in efficient compounds.
methodsExtraction of essential oils was performed using a Clevenger-type apparatus. Identification was achieved using the GC-FID technique. Confirmation was made using the GC-MS technique, and isolation was done using a preparative HPLC, equipped with an aliquots collector. The microdilution broth susceptibility assay was utilized to determine minimum inhibitory concentrations (MICs).
resultsOur in vitro study demonstrated the antibacterial activity of the Thymus syriacus Boiss essential oil and its components against the tested isolates at levels between 0.375 and 50 µl/ml. The main components of the T. syriacus essential oil were carvacrol, γ-terpinene, and ß-caryophyllene. MIC90 values for the T. syriacus essential oil against the gram-negative organisms varied between 3.125 and 12.5 µl/ml. The most effective components against the gram-negative bacteria were thymol, carvacrol, dihydro-carvon, and linalool respectively.
conclusionsThe T. syriacus essential oil and some of its components exhibited very good inhibitory effects against Syrian gram-negative isolates.
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24031109PMC3771221W1834061288What OpenQuestion holds
Registered trials
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