ReviewSeminars in immunopathology2013
The aryl hydrocarbon receptor in innate T cell immunity.
Review in Seminars in immunopathology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Intraepithelial lymphocytes in human oral diseases.Frontiers in immunology · 2025Pooled it
- Aryl Hydrocarbon Receptor in Health and Disease.MedComm · 2025Review
- Activation of the aryl hydrocarbon receptor in inflammatory bowel disease: insights from gut microbiota.Frontiers in cellular and infection microbiology · 2023Review
- Deep characterization of human γδ T cell subsets defines shared and lineage-specific traits.Frontiers in immunology · 2023Article
- Synthetic Essentiality of Tryptophan 2,3-Dioxygenase 2 in APC-Mutated Colorectal Cancer.Cancer discovery · 2022Article
- Article
- A Co-Association Network Analysis Reveals Putative Regulators for Health-Related Traits in Pigs.Frontiers in immunology · 2021Article
- Indoleamine-2,3-Dioxygenase in Thyroid Cancer Cells Suppresses Natural Killer Cell Function by Inhibiting NKG2D and NKp46 Expression via STAT Signaling Pathways.Journal of clinical medicine · 2019Article
- Dynamic Metabolic State of Tissue Resident CD8 T Cells.Frontiers in immunology · 2019Review
- The Role of the Aryl Hydrocarbon Receptor (AHR) in Immune and Inflammatory Diseases.International journal of molecular sciences · 2018Review
- Ligand-mediated cytoplasmic retention of the Ah receptor inhibits macrophage-mediated acute inflammatory responses.Laboratory investigation; a journal of technical methods and pathology · 2017Article
- γδ T cells in homeostasis and host defence of epithelial barrier tissues.Nature reviews. Immunology · 2017Review
- Choroidal γδ T cells in protection against retinal pigment epithelium and retinal injury.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2017Article
- Interleukin 17 is a chief orchestrator of immunity.Nature immunology · 2017Review
- Intestinal Barrier Interactions with Specialized CD8 T Cells.Frontiers in immunology · 2017Review
- AHR Function in Lymphocytes: Emerging Concepts.Trends in immunology · 2016Review
- 3,3'-Diindolylmethane Inhibits Flt3L/GM-CSF-induced-bone Marrow-derived CD103(+) Dendritic Cell Differentiation Regulating Phosphorylation of STAT3 and STAT5.Immune network · 2015Article
- Aryl Hydrocarbon Receptor Activation Synergistically Induces Lipopolysaccharide-Mediated Expression of Proinflammatory Chemokine (c-c motif) Ligand 20.Toxicological sciences : an official journal of the Society of Toxicology · 2015Article
- Influence of nutrient-derived metabolites on lymphocyte immunity.Nature medicine · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Recent studies highlight an important role of the aryl hydrocarbon receptor (AhR) at mucosal barriers. Surprisingly, activation of the AhR, required for the maintenance of lymphocytes as well as lymphoid architecture, can be achieved via cues derived from the external environment. This environment contains both beneficial and harmful microorganisms as well as a diverse array of compounds, and the epithelia must offer very sophisticated levels of defence. This is achieved via multifaceted immune recognition diversity and cellular complexity. Mucosal associated tissues, particularly in the gastrointestinal tract, constitute a complex immune organ for local lymphocytes and contain highly organised lymphoid structures. We will discuss the recent observations concerning the AhR in relation to the function and maintenance of innate T cells, with focus on γδ T cells found enriched at epithelial barriers.
Indexed as
Identifiers
24030775What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.