ArticleThe Journal of investigative dermatology2013
Mechanisms of contact sensitization offer insights into the role of barrier defects vs. intrinsic immune abnormalities as drivers of atopic dermatitis.
Article in The Journal of investigative dermatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed.
- Regulatory role of annexin A1 in NLRP3 inflammasome activation in atopic dermatitis: insights from keratinocytes in human and murine studies.Journal of molecular medicine (Berlin, Germany) · 2025Article
- Beyond Avoidance: Advanced Therapies for Contact Dermatitis.The journal of allergy and clinical immunology. In practice · 2024Review
- Article
- Necroptosis-mediated HMGB1 secretion of keratinocytes as a key step for inflammation development in contact hypersensitivity.Cell death discovery · 2022Article
- Anti-dermatitic effect of fermented ginseng extract including rich compound K through inhibiting activation of macrophage.Food science and biotechnology · 2019Article
- Activated Leukocyte Cell Adhesion Molecule Modulates Th2 Immune Response in Atopic Dermatitis.Allergy, asthma & immunology research · 2019Article
- Anti-inflammatory effect of aged black garlic on 12-Nutrition research and practice · 2019Article
- Salicylic acid amplifies Carbachol-induced bronchoconstriction in human precision-cut lung slices.Respiratory research · 2019Article
- The Unique Molecular Signatures of Contact Dermatitis and Implications for Treatment.Clinical reviews in allergy & immunology · 2019Review
- Lack of Endogenous Annexin A1 Increases Mast Cell Activation and Exacerbates Experimental Atopic Dermatitis.Cells · 2019Article
- Associations of TAP1 genetic polymorphisms with atopic diseases: asthma, rhinitis and dermatitis.Oncotarget · 2018Article
- Anti-inflammatory effect of galectin-1 in a murine model of atopic dermatitis.Journal of molecular medicine (Berlin, Germany) · 2017Article
- Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compounds.Scientific reports · 2016Article
- Association of HLA-DRB1 genetic variants with the persistence of atopic dermatitis.Human immunology · 2015Article
- Atopy and Sensitization to Allergens Known to Cause Systemic Contact Dermatitis.Dermatitis : contact, atopic, occupational, drugArticle
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Abstract
Atopic dermatitis (AD) is a common inflammatory skin disease characterized by wet, oozing, erythematous, pruritic lesions in the acute stage and xerotic, lichenified plaques in the chronic stage. It frequently coexists with asthma and allergic rhinitis, sharing some mechanistic features with these diseases as part of the "atopic march." Controversy exists as to whether immune abnormalities, epidermal barrier defects, or both are the primary factors responsible for disease pathogenesis. In AD patients, there is often a coexisting irritant contact dermatitis (ICD) or allergic contact dermatitis (ACD) that is sometimes clinically difficult to distinguish from AD. ACD shares molecular mechanisms with AD, including increased cellular infiltrates and cytokine activation (Gittler et al., 2013). In this issue, Newell et al. (2013) used an experimental contact sensitization model with dinitrochlorobenzene (DNCB) to gain insight into the unique immune phenotype of AD patients.
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