ArticleScience (New York, N.Y.)2013
Distinguishable epidemics of multidrug-resistant Salmonella Typhimurium DT104 in different hosts.
Article in Science (New York, N.Y.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 184 papers, 1 of them a synthesis that pooled it.
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Who cites it
184 citing papers in PubMed, 1 synthesis or guideline pooled it, 347 citations in OpenAlex.
- Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis.Lancet (London, England) · 2022Pooled it
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- Convergence of multidrug resistance, virulence, and biofilm formation in Salmonella isolates from humans, animals, and food in Xinjiang, China.BMC veterinary research · 2026Article
- Transmission of Salmonella clones between different animal species in a horse and cattle breeding region in Japan.Scientific reports · 2026Article
- Current status of antimicrobial resistance in Indian healthcare system: combating antimicrobial resistance with precision medicine.Frontiers in antibiotics · 2026Review
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- Potential links between human bloodstream infection by Salmonella enterica serovar Typhimurium and international transmission to Colombia.PLoS neglected tropical diseases · 2025Article
- ICEmST contributes to colonization of Salmonella in the intestine of piglets.Scientific reports · 2024Article
- High carriage and possible hidden spread of multidrug-resistant Salmonella among asymptomatic workers in Yulin, China.Nature communications · 2024Article
- Antimicrobial resistance and clonal relationships of Salmonella enterica Serovar Gallinarum biovar pullorum strains isolated in China based on whole genome sequencing.BMC microbiology · 2024Article
- The integrated genomic surveillance system of Andalusia (SIEGA) provides a One Health regional resource connected with the clinic.Scientific reports · 2024Article
- Characterization of a Salmonella enterica serovar Typhimurium lineage with rough colony morphology and multidrug resistance.Nature communications · 2024Article
- Comparative Gene Expression Analysis ofMicroorganisms · 2024Article
- A Retrospective Analysis ofMicroorganisms · 2024Article
- Inference of Infectious Disease Transmission through a Relaxed Bottleneck Using Multiple Genomes Per Host.Molecular biology and evolution · 2024Article
- Mobilome-driven partitions of the resistome inmSystems · 2023Article
- Relationship between the Cycle Threshold Value (Ct) of aMicroorganisms · 2023Article
124 more citing papers are in PubMed but not listed here.
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21 authors at 7 institutions in 3 countries.
Funding
Abstract
The global epidemic of multidrug-resistant Salmonella Typhimurium DT104 provides an important example, both in terms of the agent and its resistance, of a widely disseminated zoonotic pathogen. Here, with an unprecedented national collection of isolates collected contemporaneously from humans and animals and including a sample of internationally derived isolates, we have used whole-genome sequencing to dissect the phylogenetic associations of the bacterium and its antimicrobial resistance genes through the course of an epidemic. Contrary to current tenets supporting a single homogeneous epidemic, we demonstrate that the bacterium and its resistance genes were largely maintained within animal and human populations separately and that there was limited transmission, in either direction. We also show considerable variation in the resistance profiles, in contrast to the largely stable bacterial core genome, which emphasizes the critical importance of integrated genotypic data sets in understanding the ecology of bacterial zoonoses and antimicrobial resistance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.