Evidence map›Paper›PMID 24030238›Full record

Trial reportAge (Dordrecht, Netherlands)2014

Multicomponent exercises including muscle power training enhance muscle mass, power output, and functional outcomes in institutionalized frail nonagenarians.

Eduardo L Cadore, Alvaro Casas-Herrero, Fabricio Zambom-Ferraresi, Fernando Idoate, Nora Millor, Marisol Gómez, Leocadio Rodriguez-Mañas, Mikel Izquierdo

4 registry-linked trialsOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Age (Dordrecht, Netherlands), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 204 papers, 30 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
204citing papers in PubMed, 30 pooled it
35.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02918682 naunknown statusnot on this mapstarted 2019, after this paper: background citation

The Effects of a Multi-component Intervention on the Functional Capacity, Upper and Lower-body Muscle Strength, Balance and Gait in Frail Community-dwelling Older People: a Randomized Clinical Trial

TypeinterventionalSponsorUniversity of Sao PauloRan2019 to 2022Enrolled30ConditionsFrail Elderly, Exercise Therapy, Physical Therapy TechniquesArmsExercise - FIRST PHASE, Exercise - SECOND PHASE, Exercise - FOURTH PHASE, Exercise - THIRD PHASE
NCT06149871 nacompletednot on this mapstarted 2021, after this paper: background citation

Effectiveness of Individual Physical Activity Programs to Prevent and Slow Progression of Sarcopenia and Frailty Among Thai Community-dwelling Older Adults: A Double-blind Randomized Clinical Trial

TypeinterventionalSponsorMinistry of Health, ThailandRan2021 to 2022Enrolled360ConditionsSarcopenia, FrailtyArmsPhysical activity
NCT06271239 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Effect of Multicomponent Exercises on the Intrinsic Functional Capacity of Older Adults

TypeinterventionalSponsorPontificia Universidade Católica do Rio Grande do SulRan2024 to 2025Enrolled50ConditionsFrailty, Aging, Physical DisabilityArmsIntervention group (ViviFrail), Group Suggestions for a Healthy Life (CG)
NCT07076797 narecruitingnot on this mapstarted 2025, after this paper: background citation

The Effects of Lower Extremity Functional Exercise Program and Neuromuscular Electrical Nerve Stimulation on Muscle Strength, Muscle Thickness, Gait and Fall Risk in the Elderly

TypeinterventionalSponsorBiruni UniversityRan2025 to 2026Enrolled42ConditionsNeuromuscular Electrical StimulationArmsEXERCISE TRAINING, NMES
3 · Its place in the literature

Who cites it

204 citing papers in PubMed, 30 syntheses or guidelines pooled it, 515 citations in OpenAlex.

  1. Interventions for preventing falls in older people in care facilities.The Cochrane database of systematic reviews · 2025
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  13. The Effect of Resistance Training on the Rehabilitation of Elderly Patients with Sarcopenia: A Meta-Analysis.International journal of environmental research and public health · 2022
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  16. Physical and Motor Fitness Tests for Older Adults Living in Nursing Homes: A Systematic Review.International journal of environmental research and public health · 2022
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144 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Eduardo L CadoreDepartment of Health Sciences, Public University of Navarra, Campus of Tudela, Av. de Tarazona s/n, 31500, Tudela, Navarra, Spain.
Alvaro Casas-Herrero
Fabricio Zambom-Ferraresi
Fernando Idoate
Nora Millor
Marisol Gómez
Leocadio Rodriguez-Mañas
Mikel Izquierdo
Universidad de Navarra · ESComplejo Hospitalario de Navarra · ESHospital Universitario de Getafe · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This randomized controlled trial examined the effects of multicomponent training on muscle power output, muscle mass, and muscle tissue attenuation; the risk of falls; and functional outcomes in frail nonagenarians. Twenty-four elderly (91.9 ± 4.1 years old) were randomized into intervention or control group. The intervention group performed a twice-weekly, 12-week multicomponent exercise program composed of muscle power training (8-10 repetitions, 40-60 % of the one-repetition maximum) combined with balance and gait retraining. Strength and power tests were performed on the upper and lower limbs. Gait velocity was assessed using the 5-m habitual gait and the time-up-and-go (TUG) tests with and without dual-task performance. Balance was assessed using the FICSIT-4 tests. The ability to rise from a chair test was assessed, and data on the incidence and risk of falls were assessed using questionnaires. Functional status was assessed before measurements with the Barthel Index. Midthigh lower extremity muscle mass and muscle fat infiltration were assessed using computed tomography. The intervention group showed significantly improved TUG with single and dual tasks, rise from a chair and balance performance (P < 0.01), and a reduced incidence of falls. In addition, the intervention group showed enhanced muscle power and strength (P < 0.01). Moreover, there were significant increases in the total and high-density muscle cross-sectional area in the intervention group. The control group significantly reduced strength and functional outcomes. Routine multicomponent exercise intervention should be prescribed to nonagenarians because overall physical outcomes are improved in this population.

Indexed as

Frail ElderlyInstitutionalizationAccidental FallsAged, 80 and overFemaleFollow-Up StudiesGaitHumansMaleMotor ActivityMuscle, SkeletalPostural BalanceResistance TrainingSarcopeniaTreatment Outcome

Identifiers

PMID24030238
PMCPMC4039263
OpenAlexW2170739529

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.