Evidence map›Paper›PMID 24029382›Full record

ArticleTrends in microbiology2013

Fusobacterium spp. and colorectal cancer: cause or consequence?

Temitope O Keku, Amber N McCoy, Andrea M Azcarate-Peril

Abstract readComment
In one paragraph

Article in Trends in microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. The Role ofMicroorganisms · 2023
    Review
  9. Article
  10. Review
  11. Review
  12. Frontiers in nutrition · 2023
    Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Role of microbial dysbiosis in carcinogenesis & cancer therapies.The Indian journal of medical research · 2020
    Review
  19. New microbes and new infections · 2020
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Temitope O KekuCenter for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: tokeku@med.unc.edu.
Amber N McCoy
Andrea M Azcarate-Peril

Funding

PILOT AND FEASIBILITY STUDIESP30DK034987 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ANTHONY BLIKSLAGER · 1985 to 2026
$30.5M
RISK FACTORS FOR COLON ADENOMASR01CA044684 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SANDLER, ROBERT S. · 1988 to 2010
$4.6M
Intestinal Microbiota, Diet and Risk of Colorectal AdenomasR01CA136887 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KEKU, TEMITOPE O., SANDLER, ROBERT S. · 2009 to 2013
$1.5M
NCI NIH HHS R01 CA044684NCI NIH HHS R01 CA136887NIDDK NIH HHS P30 DK034987
6 · The paper itself

Abstract

Although increasing evidence suggests a relationship between bacterial dysbiosis and colorectal cancer (CRC), few studies have identified specific microbial etiologic factors. Recent studies have implicated overabundance of Fusobacterium in association with colorectal adenomas and cancer. Two articles published in Cell Host & Microbe provide insights into the Fusobacterium-CRC relationship.

Indexed as

Signal TransductionAdhesins, BacterialAnimalsbeta CateninCadherinsCarcinogenesisColorectal NeoplasmsFusobacterium nucleatumHumansVirulence FactorsAdhesins, Bacterialbeta CateninCadherinsVirulence Factors

Identifiers

PMID24029382
PMCPMC3836616

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.