GuidelineJournal of the National Comprehensive Cancer Network : JNCCN2013
Central nervous system cancers.
Guideline in Journal of the National Comprehensive Cancer Network : JNCCN, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05477316 (A Single-arm Pilot Study, to Assess the Efficacy of Cerebellar IMRT Combined With Cerebral SRS in Patients With Brain Metastases That Are Predominantly in the Posterior Fossa - a Novel Treatment Approach), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Single-arm Pilot Study, to Assess the Efficacy of Cerebellar IMRT Combined With Cerebral SRS in Patients With Brain Metastases That Are Predominantly in the Posterior Fossa - a Novel Treatment Approach
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Fractionated stereotactic radiation therapy for brain metastases: a systematic review with tumour control probability modelling.The British journal of radiology · 2017Pooled it
- Salvage therapy with bendamustine for temozolomide refractory recurrent anaplastic gliomas: a prospective phase II trial.Journal of neuro-oncology · 2017Trial
- Trial
- Natural killer T cells as therapeutic targets for neuroinflammatory disorders.Animal cells and systems · 2026Review
- Matrix Metalloproteinases in Glioma: Drivers of Invasion and Therapeutic Targets.Biotech (Basel (Switzerland)) · 2025Review
- Mortality trends of brain and central nervous system cancers in Babol, northern Iran (2013-2021).Caspian journal of internal medicine · 2025Article
- Cerebrospinal fluid: A unique source of circulating tumor DNA with broad clinical applications.Translational oncology · 2023Article
- BCG vaccination policy, natural boosting and pediatric brain and CNS tumor incidences.Frontiers in immunology · 2023Article
- Tumor-treating fields in combination with sorafenib restrain the proliferation of liver cancerOncology letters · 2022Article
- Involvement of Phytochemical-Encapsulated Nanoparticles' Interaction with Cellular Signalling in the Amelioration of Benign and Malignant Brain Tumours.Molecules (Basel, Switzerland) · 2022Review
- Oncological Ligand-Target Binding Systems and Developmental Approaches for Cancer Theranostics.Molecular biotechnology · 2021Review
- Review
- The Analysis of Human Serum N-Glycosylation in Patients with Primary and Metastatic Brain Tumors.Life (Basel, Switzerland) · 2021Article
- Upfront Brain Treatments Followed by Lung Surgery Improves Survival for Stage IV Non-small Cell Lung Cancer Patients With Brain Metastases: A Large Cohort Analysis.Frontiers in surgery · 2021Article
- Disparities in Reported Testing for 1p/19q Codeletion in Oligodendroglioma and Oligoastrocytoma Patients: An Analysis of the National Cancer Database.Frontiers in oncology · 2021Article
- Association of Innovations in Radiotherapy and Systemic Treatments With Clinical Outcomes in Patients With Melanoma Brain Metastasis From 2007 to 2016.JAMA network open · 2020Article
- Enhancing Radiotherapeutic Effect With Nanoparticle-Mediated Radiosensitizer Delivery Guided By Focused Gamma Rays In Lewis Lung Carcinoma-Bearing Mouse Brain Tumor Models.International journal of nanomedicine · 2019Article
- Combination ipilimumab and radiosurgery for brain metastases: tumor, edema, and adverse radiation effects.Journal of neurosurgery · 2018Article
- PD-1/PD-L1 and immune-related gene expression pattern in pediatric malignant brain tumors: clinical correlation with survival data in Korean population.Journal of neuro-oncology · 2018Observational
- Gamma Knife Radiosurgery for Metastatic Brain Tumors with Exophytic Hemorrhage.Journal of Korean Neurosurgical Society · 2018Article
Corrections and comments
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Authors and funding
32 authors.
Funding
Abstract
Primary and metastatic tumors of the central nervous system are a heterogeneous group of neoplasms with varied outcomes and management strategies. Recently, improved survival observed in 2 randomized clinical trials established combined chemotherapy and radiation as the new standard for treating patients with pure or mixed anaplastic oligodendroglioma harboring the 1p/19q codeletion. For metastatic disease, increasing evidence supports the efficacy of stereotactic radiosurgery in treating patients with multiple metastatic lesions but low overall tumor volume. These guidelines provide recommendations on the diagnosis and management of this group of diseases based on clinical evidence and panel consensus. This version includes expert advice on the management of low-grade infiltrative astrocytomas, oligodendrogliomas, anaplastic gliomas, glioblastomas, medulloblastomas, supratentorial primitive neuroectodermal tumors, and brain metastases. The full online version, available at NCCN. org, contains recommendations on additional subtypes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.