ReviewCurrent biology : CB2013
Building synthetic memory.
Review in Current biology : CB, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Structural determinants of soft memory in recurrent biological networks.Biophysical reviews · 2025Review
- Construction of the genetic switches in response to mannitol based on artificial MtlR box.Bioresources and bioprocessing · 2023Article
- Microbiome and Human Health: Current Understanding, Engineering, and Enabling Technologies.Chemical reviews · 2023Review
- Memory, switches, and an OR-port through bistability in chemically fueled crystals.Nature communications · 2022Article
- A synthetic distributed genetic multi-bit counter.iScience · 2021Article
- A last-in first-out stack data structure implemented in DNA.Nature communications · 2021Article
- Mechanisms and regulation underlying membraneless organelle plasticity control.Journal of molecular cell biology · 2021Review
- Dynamic bistable switches enhance robustness and accuracy of cell cycle transitions.PLoS computational biology · 2021Article
- A mechanistic model of the BLADE platform predicts performance characteristics of 256 different synthetic DNA recombination circuits.PLoS computational biology · 2020Article
- T cell fate mapping and lineage tracing technologies probing clonal aspects underlying the generation of CD8 T cell subsets.Scandinavian journal of immunology · 2020Review
- A memory switch for plant synthetic biology based on the phage ϕC31 integration system.Nucleic acids research · 2020Article
- Protein assembly systems in natural and synthetic biology.BMC biology · 2020Review
- Molecular digital data storage using DNA.Nature reviews. Genetics · 2019Review
- Biomolecular Assemblies: Moving from Observation to Predictive Design.Chemical reviews · 2018Review
- Emergent memory in cell signaling: Persistent adaptive dynamics in cascades can arise from the diversity of relaxation time-scales.Scientific reports · 2018Article
- Bottom-up approaches in synthetic biology and biomaterials for tissue engineering applications.Journal of industrial microbiology & biotechnology · 2018Article
- Mathematical model of a serine integrase-controlled toggle switch with a single input.Journal of the Royal Society, Interface · 2018Article
- Rewritable multi-event analog recording in bacterial and mammalian cells.Science (New York, N.Y.) · 2018Article
- Synthetic associative learning in engineered multicellular consortia.Journal of the Royal Society, Interface · 2017Article
- Engineering dynamical control of cell fate switching using synthetic phospho-regulons.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Cellular memory - conversion of a transient signal into a sustained response - is a common feature of biological systems. Synthetic biologists aim to understand and re-engineer such systems in a reliable and predictable manner. Synthetic memory circuits have been designed and built in vitro and in vivo based on diverse mechanisms, such as oligonucleotide hybridization, recombination, transcription, phosphorylation, and RNA editing. Thus far, building these circuits has helped us explore the basic principles required for stable memory and ask novel biological questions. Here we discuss strategies for building synthetic memory circuits, their use as research tools, and future applications of these devices in medicine and industry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.