Evidence map›Paper›PMID 24028951›Full record

ArticleCurrent biology : CB2013

Neuronal development: SAD kinases make happy axons.

Lei Xing, Jason M Newbern, William D Snider

Open access · bronzeAbstract readComment
In one paragraph

Article in Current biology : CB, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Dynamic Regulation ofInternational journal of molecular sciences · 2023
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lei XingNeuroscience Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
Jason M Newbern
William D Snider
University of North Carolina at Chapel Hill · US

Funding

Roles of Growth Factor Signaling in Neural RegenerationR01NS031768 · NINDS · WASHINGTON UNIVERSITY · PI SNIDER, WILLIAM D · 1993 to 2016
$6.7M
GSK-3 is a Master Regulator of Neural Progenitor Self-RenewalR01NS050968 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SNIDER, WILLIAM D · 2004 to 2014
$3.6M
ERK/MAPK regulation of cortical inhibitory interneuronsR00NS076661 · NINDS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI NEWBERN, JASON MARSHALL · 2013 to 2015
$726k
NINDS NIH HHS R00 NS076661NINDS NIH HHS R01 NS031768NINDS NIH HHS R01 NS050968
6 · The paper itself

Abstract

The polarity proteins LKB1 and SAD-A/B are key regulators of axon specification in the developing cerebral cortex. Recent studies now show that this mechanism cannot be generalized to other classes of neurons: instead, SAD-A/B functions downstream of neurotrophin signaling in sensory neurons to mediate a later stage of axon development - arborization in the target field.

Indexed as

AnimalsAxonsHumansNeurotrophin 3Protein Serine-Threonine KinasesSensory Receptor CellsSignal TransductionNeurotrophin 3Protein Serine-Threonine Kinases

Identifiers

PMID24028951
PMCPMC3947747
OpenAlexW2050996875

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.