Evidence map›Paper›PMID 24027614›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2012

Plasmon-controlled fluorescence and single DNA strand sequenching.

Nuriye Akbay, Krishanu Ray, Mustafa H Chowdhury, Joseph R Lakowicz

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nuriye AkbayCenter for Fluorescence Spectroscopy, University of Maryland at Baltimore, Department of Biochemistry and Molecular Biology, 725 West Lombard Street, Baltimore, MD 21201, USA.
Krishanu Ray
Mustafa H Chowdhury
Joseph R Lakowicz
University of Maryland, Baltimore · US

Funding

Metallic Surfaces and Particles in DNA AnalysisR01HG002655 · NHGRI · UNIVERSITY OF MARYLAND BALTIMORE · PI LAKOWICZ, JOSEPH R. · 2003 to 2012
$2.8M
DNA Sequencing Using Intricsic Base FluorescenceR21HG005090 · NHGRI · UNIVERSITY OF MARYLAND BALTIMORE · PI LAKOWICZ, JOSEPH R. · 2009 to 2011
$880k
Single Molecule Studies of HIV Envelope PropertiesK25AI087968 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI RAY, KRISHANU · 2011 to 2014
$443k
NHGRI NIH HHS R01 HG002655NHGRI NIH HHS R21 HG005090NIAID NIH HHS K25 AI087968
6 · The paper itself

Abstract

During the past several years we have studied the effects of metallic surfaces and nanostructures with fluorophores. We have demonstrated the metal-enhanced fluorescence (MEF) and the significant changes in the photophysical properties of fluorophores in the presence of metallic nanostructures and nanoparticles using ensemble spectroscopic studies. These studies have shown dramatic increases in brightness and photostability, especially for low quantum yield fluorophores. Much of this work was performed using visible or NIR fluorophores. In the present study, we have extended our studies to UV wavelengths and have shown that aluminum and platinum particles can enhance the emission of UV fluorophores including intrinsic protein fluorescence from 300 to 420 nm. We used the finite-difference timedomain (FDTD) method to calculate the effects of aluminum nanoparticles on nearby fluorophores that emit in the UV. And also we performed experiments to investigate the effect of metallic nanoparticles on fluorescence intensity of DNA bases and DNA G-quadruplex. We observed increase in fluorescence intensities of DNA bases varied range changing from 20 to 3-fold in steady-state fluorescence emission measurements. We obtained ~5-fold increase in fluorescence intensity of DNA G-quadruplex on both Al and Pt metallic substrates when compared with control quartz substrates.

Indexed as

DNA sequenchingfluorescencemetal enhanced fluorescencenanotechnologyplasmon controlled fluorescenceplasmonics

Identifiers

PMID24027614
PMCPMC3767000
OpenAlexW2022915457

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.