Evidence map›Paper›PMID 24027303›Full record

ArticleJournal of virology2013

Homologous recombination in E3 genes of human adenovirus species D.

Gurdeep Singh, Christopher M Robinson, Shoaleh Dehghan, Morris S Jones, David W Dyer, Donald Seto, James Chodosh

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Evolution of theVirus evolution · 2024
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  7. Article
  8. Article
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  10. Review
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  15. Article
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  17. Article
  18. Article
  19. Article
  20. Vaccine development for human mastadenovirus.Journal of thoracic disease · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Gurdeep SinghDepartment of Ophthalmology, Howe Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA.
Christopher M Robinson
Shoaleh Dehghan
Morris S Jones
David W Dyer
Donald Seto
James Chodosh
George Mason University · USMassachusetts Eye and Ear Infirmary · USHarvard University · USNaval Medical Center San Diego · USUniversity of Oklahoma Health Sciences Center · US

Funding

P30 Core Grant for Vision ResearchP30EY014104 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI Eric A Pierce · 2002 to 2026
$15.1M
Immunopathogenesis of Adenovirus KeratitisR01EY013124 · NEI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI James Chodosh, Jaya Rajaiya · 2001 to 2026
$10.8M
NEI NIH HHS EY013124NEI NIH HHS P30 EY014104NEI NIH HHS P30EY014104NEI NIH HHS R01 EY013124
6 · The paper itself

Abstract

Genes within the E3 transcription unit of human adenoviruses modulate host immune responses to infection. A comprehensive genomics and bioinformatics analysis of the E3 transcription unit for 38 viruses within human adenovirus species D (HAdV-D) revealed distinct and surprising patterns of homologous recombination. Homologous recombination was identified in open reading frames for E3 CR1α, CR1β, and CR1γ, similar to that previously observed with genes encoding the three major structural capsid proteins, the penton base, hexon, and fiber.

Indexed as

Homologous RecombinationAdenovirus E3 ProteinsAdenoviruses, HumanAdenovirus Infections, HumanCapsid ProteinsComputational BiologyDNA, ViralEvolution, MolecularGenome, ViralHumansPhylogenyAdenovirus E3 ProteinsCapsid ProteinsDNA, Viral

Identifiers

PMID24027303
PMCPMC3807923
OpenAlexW2010948073

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.