Trial reportThe Journal of neuroscience : the official journal of the Society for Neuroscience2013
Transfer of cognitive training across magnitude dimensions achieved with concurrent brain stimulation of the parietal lobe.
Trial report in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 63 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Improving Math Deficits in Children With Dyscalculia by tRNS: a Randomized, Double-blind Study
Comparing the Efficacy of tDCS and tRNS to Improve Reading Skills in Children and Adolescents With Dyslexia
Who cites it
63 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Online HD-tRNS Over the Right Temporoparietal Junction Modulates Social Inference But Not Motor Coordination.eNeuro · 2025Trial
- Transcranial random noise stimulation combined with cognitive training for treating ADHD: a randomized, sham-controlled clinical trial.Translational psychiatry · 2023Trial
- Performance after training in a complex cognitive task is enhanced by high-definition transcranial random noise stimulation.Scientific reports · 2022Trial
- Boosting Learning Efficacy with Noninvasive Brain Stimulation in Intact and Brain-Damaged Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Trial
- Trial
- Dissociating mechanisms of spatial suppression and summation in human visual cortical regions MT/V5: a transcranial Direct Current Stimulation (tDCS) study and clinical implications.International review of psychiatry (Abingdon, England) · 2026Article
- Occipital and parietal non-invasive brain stimulation enhances perceptual learning and transfer: evidence from high-frequency tRNS.Frontiers in neuroscience · 2026Article
- Effects on nonverbal numerical acuity performance after a single-session transient random noise stimulation over the intraparietal sulcus or dorsolateral prefrontal cortex.Scientific reports · 2025Article
- No facilitatory effects of transcranial random noise stimulation on motion processing: A registered report.Cortex; a journal devoted to the study of the nervous system and behavior · 2025Article
- Functional connectivity and GABAergic signaling modulate the enhancement effect of neurostimulation on mathematical learning.PLoS biology · 2025Article
- Effective engagement in computerized cognitive training for older adults.Ageing research reviews · 2025Review
- Stimulating prefrontal cortex facilitates training transfer by increasing representational overlap.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Cellular mechanisms underlying carry-over effects after magnetic stimulation.Scientific reports · 2024Article
- Effects of online tDCS and hf-tRNS on reading performance in children and adolescents with developmental dyslexia: a study protocol for a cross sectional, within-subject, randomized, double-blind, and sham-controlled trial.Frontiers in neurology · 2024Article
- Transcranial Direct Current Stimulation in neurogenetic syndromes: new treatment perspectives for Down syndrome?Frontiers in cellular neuroscience · 2024Article
- Human neuronal excitation/inhibition balance explains and predicts neurostimulation induced learning benefits.PLoS biology · 2023Article
- The more numerous the longer: how the integration between numerosity and time leads to a common neural response.Proceedings. Biological sciences · 2023Article
- 10 Minutes Frontal 40 Hz tACS-Effects on Working Memory Tested by Luck-Vogel Task.Behavioral sciences (Basel, Switzerland) · 2022Article
- Do Executive Dysfunction, Delay Aversion, and Time Perception Deficit Predict ADHD Symptoms and Early Academic Performance in Preschoolers.Research on child and adolescent psychopathology · 2022Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Improvement in performance following cognitive training is known to be further enhanced when coupled with brain stimulation. Here we ask whether training-induced changes can be maintained long term and, crucially, whether they can extend to other related but untrained skills. We trained overall 40 human participants on a simple and well established paradigm assessing the ability to discriminate numerosity--or the number of items in a set--which is thought to rely on an "approximate number sense" (ANS) associated with parietal lobes. We coupled training with parietal stimulation in the form of transcranial random noise stimulation (tRNS), a noninvasive technique that modulates neural activity. This yielded significantly better and longer lasting improvement (up to 16 weeks post-training) of the precision of the ANS compared with cognitive training in absence of stimulation, stimulation in absence of cognitive training, and cognitive training coupled to stimulation to a control site (motor areas). Critically, only ANS improvement induced by parietal tRNS + Training transferred to proficiency in other parietal lobe-based quantity judgment, i.e., time and space discrimination, but not to quantity-unrelated tasks measuring attention, executive functions, and visual pattern recognition. These results indicate that coupling intensive cognitive training with tRNS to critical brain regions resulted not only in the greatest and longer lasting improvement of numerosity discrimination, but importantly in this enhancement being transferable when trained and untrained abilities are carefully chosen to share common cognitive and neuronal components.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.