ArticleJournal of neurophysiology2013
Optical imaging of cortical networks via intracortical microstimulation.
Article in Journal of neurophysiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 40 citations in OpenAlex.
- Mid-Infrared Light Exhibits Tissue-Specific Transmittance and Modulates Neural Signal Conduction Along Axons.Neuroscience bulletin · 2026Article
- Characterizing Evoked Movement Patterns and Connectivity in Sensorimotor Cortex After Sensory Loss in Squirrel Monkeys.The Journal of comparative neurology · 2025Article
- Activation and depression of neural and hemodynamic responses induced by the intracortical microstimulation and visual stimulation in the mouse visual cortex.Journal of neural engineering · 2024Article
- Differential impact of unilateral stroke on the bihemispheric motor cortex representation of the jaw and tongue muscles in young and aged rats.Frontiers in neurology · 2024Article
- Stimulation-Evoked Effective Connectivity (SEEC): An in-vivo approach for defining mesoscale corticocortical connectivity.Journal of neuroscience methods · 2023Article
- Optogenetic stimulation of the primary visual cortex drives activity in the visual association cortex.Current research in neurobiology · 2023Article
- Mapping mesoscale cortical connectivity in monkey sensorimotor cortex with optical imaging and microstimulation.The Journal of comparative neurology · 2020Article
- In vivo microstimulation with cathodic and anodic asymmetric waveforms modulates spatiotemporal calcium dynamics in cortical neuropil and pyramidal neurons of male mice.Journal of neuroscience research · 2020Article
- Principles of Intrinsic Motor Cortex Connectivity in Primates.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Article
- Representations of Fine Digit Movements in Posterior and Anterior Parietal Cortex Revealed Using Long-Train Intracortical Microstimulation in Macaque Monkeys.Cerebral cortex (New York, N.Y. : 1991) · 2018Article
- Spatio-temporal characteristics of population responses evoked by microstimulation in the barrel cortex.Scientific reports · 2018Article
- Electrical Stimulation of Visual Cortex: Relevance for the Development of Visual Cortical Prosthetics.Annual review of vision science · 2017Review
- Mesoscale Mapping of Mouse Cortex Reveals Frequency-Dependent Cycling between Distinct Macroscale Functional Modules.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Saturation in Phosphene Size with Increasing Current Levels Delivered to Human Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Review of functional and clinical relevance of intrinsic signal optical imaging in human brain mapping.Neurophotonics · 2017Review
- Microelectrode array stimulation combined with intrinsic optical imaging: A novel tool for functional brain mapping.Journal of neuroscience methods · 2016Article
- Mapping Horizontal Spread of Activity in Monkey Motor Cortex Using Single Pulse Microstimulation.Frontiers in neural circuits · 2016Article
- Discriminability of Single and Multichannel Intracortical Microstimulation within Somatosensory Cortex.Frontiers in bioengineering and biotechnology · 2016Article
- Spatiotemporal Profile of Voltage-Sensitive Dye Responses in the Visual Cortex of Tree Shrews Evoked by Electric Microstimulation of the Dorsal Lateral Geniculate and Pulvinar Nuclei.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Understanding cortical organization is key to understanding brain function. Distinct neural networks underlie the functional organization of the cerebral cortex; however, little is known about how different nodes in the cortical network interact during perceptual processing and motor behavior. To study cortical network function we examined whether the optical imaging of intrinsic signals (OIS) reveals the functional patterns of activity evoked by electrical cortical microstimulation. We examined the effects of current amplitude, train duration, and depth of cortical stimulation on the hemodynamic response to electrical microstimulation (250-Hz train, 0.4-ms pulse duration) in anesthetized New World monkey somatosensory cortex. Electrical stimulation elicited a restricted cortical response that varied according to stimulation parameters and electrode depth. Higher currents of stimulation recruited more areas of cortex than smaller currents. The largest cortical responses were seen when stimulation was delivered around cortical layer 4. Distinct local patches of activation, highly suggestive of local projections, around the site of stimulation were observed at different depths of stimulation. Thus we find that specific electrical stimulation parameters can elicit activation of single cortical columns and their associated columnar networks, reminiscent of anatomically labeled networks. This novel functional tract tracing method will open new avenues for investigating relationships of local cortical organization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.