ReviewPediatric nephrology (Berlin, Germany)2014
Recreating kidney progenitors from pluripotent cells.
Review in Pediatric nephrology (Berlin, Germany), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Extracellular Microenvironmental Control for Organoid Assembly.Tissue engineering. Part B, Reviews · 2022Review
- Laminin 411 mediates endothelial specification via multiple signaling axes that converge on β-catenin.Stem cell reports · 2022Article
- Vascular deficiencies in renal organoids and ex vivo kidney organogenesis.Developmental biology · 2021Article
- Bioprinting of 3D Convoluted Renal Proximal Tubules on Perfusable Chips.Scientific reports · 2016Article
- Generation of kidney organoids from human pluripotent stem cells.Nature protocols · 2016Article
- Generating kidney tissue from pluripotent stem cells.Cell death discovery · 2016Review
- Bioengineering and Stem Cell Technology in the Treatment of Congenital Heart Disease.Journal of clinical medicine · 2015Review
- Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney.Nature cell biology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Access to human pluripotent cells theoretically provides a renewable source of cells that can give rise to any required cell type for use in cellular therapy or bioengineering. However, successfully directing this differentiation remains challenging for most desired endpoints cell type, including renal cells. This challenge is compounded by the difficulty in identifying the required cell type in vitro and the multitude of renal cell types required to build a kidney. Here we review our understanding of how the embryo goes about specifying the cells of the kidney and the progress to date in adapting this knowledge for the recreation of nephron progenitors and their mature derivatives from pluripotent cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.