Trial reportQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2014
Quality of life among hazardous and harmful drinkers: EQ-5D over a 1-year follow-up period.
Trial report in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Psychological interventions for co-occurring depression and substance use disorders.The Cochrane database of systematic reviews · 2019Pooled it
- Personalised digital interventions for reducing hazardous and harmful alcohol consumption in community-dwelling populations.The Cochrane database of systematic reviews · 2017Pooled it
- Can The EQ-5D Detect Meaningful Change? A Systematic Review.PharmacoEconomics · 2015Pooled it
- The effect of exercise as adjunctive treatment on quality of life for individuals with alcohol use disorders: a randomized controlled trial.BMC public health · 2019Trial
- Trial
- Counselling for Alcohol Problems (CAP), a lay counsellor-delivered brief psychological treatment for harmful drinking in men, in primary care in India: a randomised controlled trial.Lancet (London, England) · 2017Trial
- Trial
- Informing low-risk drinking guidelines: a secondary, cross-sectional data analysis of alcohol use and health utility.Addiction science & clinical practice · 2026Article
- Health-related quality of life in patients with alcohol use disorder: comparing instruments and mapping from clinical measures to preference-based measures.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Gender differences in the relationship between alcohol use patterns and health-related quality of life in a population experiencing a recent surge in harmful alcohol use among females: the 2018 National survey in Taiwan.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Substance use in childhood and adolescence and its associations with quality of life and behavioral strengths and difficulties.BMC public health · 2022Article
- The association between personal social capital and health-related quality of life among Chinese older people: A cross-sectional study.Frontiers in nutrition · 2022Article
- SF-6D utility scores for alcohol use disorder status and alcohol consumption risk levels in the US population.Addiction (Abingdon, England) · 2021Article
- Health-related quality of life of alcohol use disorder with co-occurring conditions in the US population.Drug and alcohol dependence · 2021Article
- Measuring intangible cost-of-morbidity due to substance dependence: implications of using alternative preference-based instruments.The European journal of health economics : HEPAC : health economics in prevention and care · 2020Article
- Article
- Web-Based Self-Help for Problematic Alcohol Use: a Large Naturalistic Study.International journal of behavioral medicine · 2017Observational
- Validation of the AUDIT-C in adults seeking help with their drinking online.Addiction science & clinical practice · 2017Article
- Perceived quality of life, 6 months after detoxification: Is abstinence a modifying factor?Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016Article
- Population norms for the EQ-5D index scores using Singapore preference weights.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
purposeTo investigate the ability of the EQ-5D to discriminate between levels of alcohol risk in a large sample of hazardous and harmful drinkers, and to explore the relationship between transitions between alcohol risk levels and changes in EQ-5D up to 12 months.
methodsThis is a web-based randomised controlled trial evaluating a novel intervention for hazardous and harmful alcohol consumption. EQ-5D scores were compared among groups of drinkers at baseline (low/medium/high risk according to self-reported past week alcohol consumption), and changes in EQ-5D scores were estimated as a function of changes in alcohol consumption level.
resultsBaseline EQ-5D scores were dominated by problems with anxiety/depression, which increased with alcohol risk level, whilst high-risk drinkers also experienced more problems with physical HRQoL dimensions. However, the tool demonstrated a considerable ceiling effect. At follow-up, despite considerable reductions in alcohol consumption across the sample, significant changes in aggregated EQ-5D index scores were only observed for high-risk drinkers at baseline who reduced their drinking, with small improvements (0.04-0.06) compared to those who did not reduce.
conclusionsOur results suggest that the three-option EQ-5D may not be an optimal primary end point for measuring clinical and cost-effectiveness in randomised controlled trials of interventions among hazardous and harmful alcohol users, although further testing of the sensitivity of the tool in these populations is needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.