ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2013
Hybrid myocardial imaging for risk stratification prior to kidney transplantation: added value of coronary calcium and epicardial adipose tissue.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Correlation Between Epicardial Adipose Tissue and PET Cardiac Perfusion: A Systematic Review.Medical sciences (Basel, Switzerland) · 2026Pooled it
- Perirenal fat differs in patients with chronic kidney disease receiving different vitamin D-based treatments: a preliminary study.BMC nephrology · 2025Article
- C-peptide and epicardial adipose tissue in dialysis-dependent chronic kidney disease patients.Frontiers in medicine · 2025Article
- Computed tomography measured epicardial adipose tissue and psoas muscle attenuation: new biomarkers to predict major adverse cardiac events (MACE) and mortality in patients with heart disease and critically ill patients. Part I: Epicardial adipose tissue.Anaesthesiology intensive therapy · 2023Article
- Cardiac Imaging and Management of Cardiac Disease in Asymptomatic Renal Transplant Candidates: A Current Update.Diagnostics (Basel, Switzerland) · 2022Review
- Cardiorenal Fat: A Cardiovascular Risk Factor With Implications in Chronic Kidney Disease.Frontiers in medicine · 2021 · on this mapReview
- Trial design and baseline characteristics of CaLIPSO: a randomized, double-blind placebo-controlled trial of SNF472 in patients receiving haemodialysis with cardiovascular calcification.Clinical kidney journal · 2021Article
- Epicardial Adipose Tissue, Adiponectin and Leptin: A Potential Source of Cardiovascular Risk in Chronic Kidney Disease.International journal of molecular sciences · 2020Review
- Perirenal fat thickness is associated with metabolic risk factors in patients with chronic kidney disease.Kidney research and clinical practice · 2019Article
- Prognostic Utility of Calcium Scoring as an Adjunct to Stress Myocardial Perfusion Scintigraphy in End-Stage Renal Disease.The American journal of cardiology · 2016Article
- Serum paraoxonase activity is associated with epicardial fat tissue in renal transplant recipients.International urology and nephrology · 2015Article
- Does hybrid imaging have a role in cardiac risk evaluation of the pre-renal transplant patient?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPatient selection and optimal approach to risk stratification prior to kidney transplantation remain uncertain. We sought new predictors of an abnormal myocardial perfusion (MYP) stress test result.
methodsRetrospective study of 411 consecutive chronic kidney disease stages 4-5D patients awaiting kidney transplantation referred for risk stratification. PET-CT or SPECT-CT was used to assess MYP and quantify coronary artery calcium (CAC) and epicardial adipose tissue (EAT). Abnormal MYP was defined as a perfusion defect involving ≥5% of the left ventricular myocardium.
resultsFixed or reversible MYP defects were present in 41 patients (10%). Male sex, smoking, and history of cardiovascular disease were more prevalent; age was higher and CAC and EAT were greater in patients with MYP defects than in those with normal MYP. On multivariate logistic regression, EAT and CAC were independent predictors of abnormal MYP while diabetes mellitus showed a borderline association (P = .08). EAT added incremental diagnostic value to a model including age, CAC and diabetes mellitus [AUC 0.73 (95% CI 0.64-0.81) to 0.76 (95% CI 0.68-0.84; P = .02)]. Furthermore, the model containing EAT showed improved diagnostic discrimination.
conclusionsAbnormal MYP on screening stress testing appears to be rare in patients awaiting kidney transplantation suggesting an excess of testing. EAT and CAC may help predict what patients are at higher risk of developing abnormalities of MYP under stress.
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