ArticleJournal of gastroenterology2014
Quantitative analysis of diagnosing pancreatic fibrosis using EUS-elastography (comparison with surgical specimens).
Article in Journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed, 104 citations in OpenAlex.
- Utility of endoscopic ultrasonography elastography as a predictive tool for post-treatment recurrence of resectable pancreatic cancer treated with neoadjuvant and adjuvant chemotherapy: a retrospective study in Japan.Clinical endoscopy · 2026Article
- Identifying intact and fibrotic parenchyma in pancreatic ductal adenocarcinomas using compression optical coherence elastography.Scientific reports · 2026Article
- Preoperative Endoscopic Ultrasound Strain Elastography Has Limited Value for Predicting Intraoperative Pancreatic Texture: A Single-Operator Pilot Study.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
- Article
- Assessing Pancreatic Morphology via Endosonography in Alcohol-Induced Chronic Liver Disease.Sisli Etfal Hastanesi tip bulteni · 2025Article
- Point-shear wave elastography generated by acoustic radiation force impulse in chronic pancreatitis.United European gastroenterology journal · 2024Article
- The diagnostic accuracy of endoscopic ultrasound-shear wave elastography in multiple pancreatic regions for chronic pancreatitis based on the Rosemont criteria.Journal of medical ultrasonics (2001) · 2023Article
- Radiological parameters to predict pancreatic texture: Current evidence and future perspectives.World journal of radiology · 2023Review
- Fibrosis in Liver and Pancreas: a Review on Pathogenic Significance, Diagnostic Options, and Current Management Strategies.Inflammation · 2023Review
- Endoscopic Ultrasound (EUS) Guided Elastography.Diagnostics (Basel, Switzerland) · 2023Review
- Review
- Endoscopic Ultrasound Advanced Techniques for Diagnosis of Gastrointestinal Stromal Tumours.Cancers · 2023Review
- The role of EUS elastography-guided fine needle biopsy in the histological diagnosis of solid pancreatic lesions: a prospective exploratory study.Scientific reports · 2022Article
- The expanding role of endoscopic ultrasound elastography.Clinical journal of gastroenterology · 2022Review
- Applications of endoscopic ultrasound elastography in pancreatic diseases: From literature to real life.World journal of gastroenterology · 2022Review
- Current status of the diagnosis of chronic pancreatitis by ultrasonographic elastography.The Korean journal of internal medicine · 2022Review
- Recent Advances in Endosonography-Elastography: Literature Review.Journal of clinical medicine · 2021Review
- Comprehensive review of diagnostic modalities for early chronic pancreatitis.World journal of gastroenterology · 2021Review
- Variability measurements provide additional value to shear wave elastography in the diagnosis of pancreatic cancer.Scientific reports · 2021Article
- An Autopsy Case of Anaplastic Carcinoma of the Pancreas in a 39-Year-Old Woman that Developed from Hereditary Pancreatitis.The American journal of case reports · 2021Article
Corrections and comments
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Authors and funding
19 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAn accurate diagnosis of pancreatic fibrosis is clinically important and may have potential for staging chronic pancreatitis. The aim of this study was to diagnose the grade of pancreatic fibrosis through a quantitative analysis of endoscopic ultrasound elastography (EUS-EG).
methodsFrom September 2004 to October 2010, 58 consecutive patients examined by EUS-EG for both pancreatic tumors and their upstream pancreas before pancreatectomy were enrolled. Preoperative EUS-EG images in the upstream pancreas were statistically quantified, and the results were retrospectively compared with postoperative histological fibrosis in the same area. For the quantification of EUS-EG images, 4 parameters (mean, standard deviation, skewness, and kurtosis) were calculated using novel software. Histological fibrosis was graded into 4 categories (normal, mild fibrosis, marked fibrosis, and severe fibrosis) according to a previously reported scoring system.
resultsThe fibrosis grade in the upstream pancreas was normal in 24 patients, mild fibrosis in 19, marked fibrosis in 6, and severe fibrosis in 9. Fibrosis grade was significantly correlated with all 4 quantification parameters (mean r = -0.75, standard deviation r = -0.54, skewness r = 0.69, kurtosis r = 0.67). According to the receiver operating characteristic analysis, the mean was the most useful parameter for diagnosing pancreatic fibrosis. Using the mean, the area under the ROC curves for the diagnosis of mild or higher-grade fibrosis, marked or higher-grade fibrosis and severe fibrosis were 0.90, 0.90, and 0.90, respectively.
conclusionsAn accurate diagnosis of pancreatic fibrosis may be possible by analyzing EUS-EG images.
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