Evidence map›Paper›PMID 24026071›Full record

ReviewAmerican journal of physiology. Regulatory, integrative and comparative physiology2013

Vitamin D and the heart.

David G Gardner, Songcang Chen, Denis J Glenn

Open access · greenAbstract readReview
In one paragraph

Review in American journal of physiology. Regulatory, integrative and comparative physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 71 citations in OpenAlex.

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  13. Protective role of vitamin D3 in a rat model of hyperthyroid-induced cardiomyopathy.Journal of traditional and complementary medicine · 2023
    Article
  14. Article
  15. The role of vitamin D in cardiovascular disease and COVID-19.Reviews in endocrine & metabolic disorders · 2022
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

David G GardnerDiabetes Center, University of California at San Francisco, San Francisco, California; and.
Songcang Chen
Denis J Glenn
University of California, San Francisco · US

Funding

REGULATION OF ANP RECEPTOR ACTIVITY IN VASCULAR CELLSR01HL045637 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GARDNER, DAVID G · 1992 to 2011
$3.6M
A Role for Non-Hypercalcemic VDR Agonists in the Control of VSMC ProliferationR21HL096047 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHEN, SONGCANG · 2010 to 2011
$425k
Characterization of the Vitamin D System in Normal and Hypertrophied HeartF32HL086158 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GLENN, DENIS J · 2006 to 2008
$110k
NHLBI NIH HHS F32 HL086158NHLBI NIH HHS HL-086158NHLBI NIH HHS HL-096047NHLBI NIH HHS HL-45637NHLBI NIH HHS R01 HL045637NHLBI NIH HHS R21 HL096047
6 · The paper itself

Abstract

Vitamin D receptors (VDR) are found in cells throughout the cardiovascular system. A variety of experimental studies indicate that the liganded VDR may play an important role in controlling cardiac hypertrophy and fibrosis, regulating blood pressure, and suppressing the development of atherosclerosis. Some, but not all, observational studies in humans provide support for these experimental findings, raising the possibility that vitamin D or its analogs might prove useful therapeutically in the prevention or treatment of cardiovascular disease.

Indexed as

AnimalsCardiovascular DiseasesHumansLigandsMyocardiumReceptors, CalcitriolSignal TransductionVitamin DLigandsReceptors, CalcitriolVitamin Dheartvitamin D

Identifiers

PMID24026071
PMCPMC3840320
OpenAlexW1980254368

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.