Evidence map›Paper›PMID 24025114›Full record

ArticleAddiction (Abingdon, England)2014

Non-medical use of prescription opioids during the transition to adulthood: a multi-cohort national longitudinal study.

Sean Esteban McCabe, John E Schulenberg, Patrick M O'Malley, Megan E Patrick, Deborah D Kloska

Registry-linked trialAbstract read
In one paragraph

Article in Addiction (Abingdon, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04528173 (Opioid-Free Versus Transitional Anesthetic With Opioids From Tonsillectomy), which is not on this map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04528173 phase4terminatednot on this mapstarted 2020, after this paper: background citation

Opioid-Free Versus Transitional Anesthetic With Opioids From Tonsillectomy

TypeinterventionalSponsorChildren's Hospital of PhiladelphiaRan2020 to 2023Enrolled35ConditionsAnesthesia, Opioid Use, Tonsillitis, Sleep DisorderArmsKetorolac, Dexmedetomidine, Morphine, Fentanyl
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Psychological/behavioral interventions for emerging adults with chronic pain.Frontiers in pain research (Lausanne, Switzerland) · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Prescription Drug Misuse: Taking a Lifespan Perspective.Substance abuse : research and treatment · 2020
    Review
  13. Article
  14. Barriers to accurately assessing prescription opioid misuse on surveys.The American journal of drug and alcohol abuse · 2019
    Article
  15. Review
  16. Observational
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sean Esteban McCabeSubstance Abuse Research Center, University of Michigan, Ann Arbor, MI, USA; Institute for Research on Women and Gender, University of Michigan, Ann Arbor, MI, USA.
John E Schulenberg
Patrick M O'Malley
Megan E Patrick
Deborah D Kloska

Funding

Monitoring the Future: Drug Use & Lifestyles of American Youth (Supp1: Nicotine Pouch and E-cigarette Use Among US Adolescents: National Estimates of Brand Use and Flavor Preferences)R01DA001411 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Richard A Miech · 1985 to 2026
$144.9M
Monitoring the Future: A Cohort-Sequential Panel Study of Drug Use, Ages 19-65 - Diversity Supplement (Solberg)R01DA016575 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Megan E. Patrick · 2003 to 2026
$44.6M
Trajectories of Prescription Nonmedical Drug MisuseR01DA031160 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEAN ESTEBAN MCCABE · 2011 to 2026
$3.7M
A Prospective Study of the Nonmedical use of Prescription Medications by AdolesceR01DA024678 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOYD, CAROL J · 2009 to 2013
$3.0M
NIDA NIH HHS R01 DA001411NIDA NIH HHS R01DA001411NIDA NIH HHS R01 DA016575NIDA NIH HHS R01DA016575NIDA NIH HHS R01 DA024678NIDA NIH HHS R01DA024678NIDA NIH HHS R01 DA031160NIDA NIH HHS R01DA031160
6 · The paper itself

Abstract

aimsTo examine non-medical use of prescription opioids (NMUPO) patterns during the transition from adolescence to adulthood, and assess individual characteristics and other substance use behaviors associated with longitudinal patterns of NMUPO.

designNationally representative samples of high school seniors in the United States (wave 1: modal age 18 years) were followed longitudinally across three biennial follow-up waves (waves 2, 3 and 4: modal ages 19/20, 21/22 and 23/24 years).

settingData were collected via self-administered questionnaires to high school seniors and young adults.

participantsThe longitudinal sample consisted of 27 268 individuals in 30 cohorts (high school senior years 1976-2005) who participated in all four waves. MEASUREMENTS: Self-reports of NMUPO and other substance use behaviors.

findingsApproximately 11.6% [95% confidence interval (CI) = 11.2%, 12.0%] of the sample reported past-year NMUPO in at least one of the four waves. Among those who reported past-year NMUPO in at least one wave, 69.0% (67.6%, 70.4%), 20.5% (19.3%, 21.7%), 7.8% (7.1%, 8.6%) and 2.7% (2.3%, 3.1%) reported NMUPO at one, two, three and four waves, respectively. Several wave 1 variables were associated with greater odds of multiple waves of NMUPO and individuals who reported more waves of NMUPO had greater odds of other substance use behaviors.

conclusionsAlthough most non-medical use of prescription opioids among 18-year-olds in the United States appears to be non-continuing, approximately one-third of the sample reporting non-medical use of prescription opioids appear to continue use beyond age 18 and have elevated odds of other substance use behaviors at ages 23/24.

Indexed as

Analgesics, OpioidAdolescentCohort StudiesFemaleHumansLongitudinal StudiesMaleOpioid-Related DisordersPrescription Drug MisuseSubstance-Related DisordersUnited StatesYoung AdultAnalgesics, OpioidAdolescentsepidemiologylongitudinalnon‐medical useprescription opioidssubstance use

Identifiers

PMID24025114
PMCPMC3930150

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.