Evidence map›Paper›PMID 24024953›Full record

ArticleJournal of the American Chemical Society2013

Temperature-activated nucleic acid nanostructures.

Ke Zhang, Xiao Zhu, Fei Jia, Evelyn Auyeung, Chad A Mirkin

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. CeOAsian journal of pharmaceutical sciences · 2025
    Article
  3. Review
  4. Article
  5. Functional DNA-Polymer Conjugates.Chemical reviews · 2021
    Review
  6. Interlocked DNA Nanojoints for Reversible Thermal Sensing.Angewandte Chemie (International ed. in English) · 2020
    Article
  7. Article
  8. Light-enabled reversible self-assembly and tunable optical properties of stable hairy nanoparticles.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ke ZhangDepartment of Chemistry and Chemical Biology, Northeastern University , 360 Huntington Ave, Boston, Massachusetts 02115, United States.
Xiao Zhu
Fei Jia
Evelyn Auyeung
Chad A Mirkin

Funding

Theranostic Magnetic Nanostructures for the Molecular Imaging of CancerU54CA151880 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MIRKIN, CHAD A. · 2010 to 2014
$11.5M
NCI NIH HHS U54 CA151880
6 · The paper itself

Abstract

DNA and poly(N-isopropylacrylamide) are co-assembled onto gold nanoparticles. The DNA sequences can be reversibly exposed or hidden from the polymer surface in response to temperature cues, thereby translating the temperature trigger to the on-off switching of the surface chemistry and function. When exposed by heating (∼30 °C), the DNA rapidly hybridizes to complementary strands, and chain-end biotin groups become readily accessible, while at lower temperatures these activities are largely blocked.

Indexed as

GoldMetal NanoparticlesAcrylic ResinsDNATemperatureAcrylic ResinsDNAGoldpoly-N-isopropylacrylamide

Identifiers

PMID24024953
PMCPMC3865851

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.