ReviewAnnual review of microbiology2013
Experimental approaches for defining functional roles of microbes in the human gut.
Review in Annual review of microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Towards ecological psychiatry: The herbicide glyphosate disrupts behavior through microbiota-gut-brain axis.Molecular psychiatry · 2026Article
- The Importance of Sociality and Diet in Explaining Variation in the Bonobo Gut Microbiota.American journal of primatology · 2026Article
- Endogenous Ethanol Metabolism and Development of MASLD-MASH.International journal of molecular sciences · 2025Review
- The impact of the human gut microbiome on the treatment of autoimmune disease.Immunological reviews · 2024Review
- Advanced computational tools, artificial intelligence and machine-learning approaches in gut microbiota and biomarker identification.Frontiers in medical technology · 2024Review
- Discovery and delivery strategies for engineered live biotherapeutic products.Trends in biotechnology · 2022Review
- Emerging computational paradigms to address the complex role of gut microbial metabolism in cardiovascular diseases.Frontiers in cardiovascular medicine · 2022Review
- Comparative analysis of oral-gut microbiota between captive and wild long-tailed macaque in Thailand.Scientific reports · 2021Article
- Effects of Antibiotics on the Intestinal Microbiota of Mice.Antibiotics (Basel, Switzerland) · 2020Article
- Expansion of known ssRNA phage genomes: From tens to over a thousand.Science advances · 2020Article
- Regulating vitamin B12 biosynthesis via theProceedings of the National Academy of Sciences of the United States of America · 2020Article
- Evolutionary and ecological consequences of gut microbial communities.Annual review of ecology, evolution, and systematics · 2019Article
- Holobionts and ecological speciation: the intestinal microbiota of lake whitefish species pairs.Microbiome · 2018Article
- Role of gut microbiota in intestinal wound healing and barrier function.Tissue barriers · 2018Review
- Article
- Atlantic Salmon (Salmo salar L.) Gastrointestinal Microbial Community Dynamics in Relation to Digesta Properties and Diet.Microbial ecology · 2016Article
- Hyperexpansion of RNA Bacteriophage Diversity.PLoS biology · 2016Article
- Linking Biosynthetic Gene Clusters to their Metabolites via Pathway- Targeted Molecular Networking.Current topics in medicinal chemistry · 2016Review
- Bridging the knowledge gap: from microbiome composition to function.Molecular systems biology · 2015Article
- The role of the gut microbiota in the pathogenesis of antiphospholipid syndrome.Current rheumatology reports · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The complex and intimate relationship between humans and their gut microbial communities is becoming less obscure, due in part to large-scale gut microbial genome-sequencing projects and culture-independent surveys of the composition and gene content of these communities. These studies build upon, and are complemented by, experimental efforts to define underlying mechanisms of host-microbe interactions in simplified model systems. This review highlights the intersection of these approaches. Experimental studies now leverage the advances in high-throughput DNA sequencing that have driven the explosion of microbial genome and community profiling projects, and the loss-of-function and gain-of-function strategies long employed in model organisms are now being extended to microbial genes, species, and communities from the human gut. These developments promise to deepen our understanding of human gut host-microbiota relationships and are readily applicable to other host-associated and free-living microbial communities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.