ArticleBioMed research international2013
Dissolution of silver nanowires and nanospheres dictates their toxicity to Escherichia coli.
Article in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Preparation of nanosilver/polymer composites and evaluation of their antimicrobial and antitumor effect.RSC advances · 2025Article
- Particle-Driven Effects at the Bacteria Interface: A Nanosilver Investigation of Particle Shape and Dose Metric.ACS applied materials & interfaces · 2023Article
- Enhancement of Antibacterial Performance of Silver Nanowire Transparent Film by Post-Heat Treatment.Nanomaterials (Basel, Switzerland) · 2020Article
- Evaluation of Antibacterial and Cytotoxicity Properties of Silver Nanowires and Their Composites with Carbon Nanotubes for Biomedical Applications.International journal of molecular sciences · 2020Article
- Rapid in situ assessment of Cu-ion mediated effects and antibacterial efficacy of copper surfaces.Scientific reports · 2018Article
- AgNPs Change Microbial Community Structures of Wastewater.Frontiers in microbiology · 2018Article
- Current Knowledge on the Use of Computational Toxicology in Hazard Assessment of Metallic Engineered Nanomaterials.International journal of molecular sciences · 2017Review
- Effects of silver nanowire length and exposure route on cytotoxicity to earthworms.Environmental science and pollution research international · 2017Article
- Article
- Mutagenic Effects of Nanosilver Consumer Products: a new Approach to Physicochemical Properties.Iranian journal of pharmaceutical research : IJPR · 2015Article
- Aquatic Toxicity Comparison of Silver Nanoparticles and Silver Nanowires.BioMed research international · 2015Article
- Short versus long silver nanowires: a comparison of in vivo pulmonary effects post instillation.Particle and fibre toxicology · 2014Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Silver nanoparticles are extensively used in antibacterial applications. However, the mechanisms of their antibacterial action are not yet fully explored. We studied the solubility-driven toxicity of 100 × 6100 nm (mean primary diameter × length) silver nanowires (NWs) to recombinant bioluminescent Escherichia coli as a target representative of enteric pathogens. The bacteria were exposed to silver nanostructures in water to exclude the speciation-driven alterations. Spherical silver nanoparticles (83 nm mean primary size) were used as a control for the effect of NPs shape. Toxicity of both Ag NWs and spheres to E. coli was observed at similar nominal concentrations: the 4h EC50 values, calculated on the basis of inhibition of bacterial bioluminescence, were 0.42 ± 0.06 and 0.68 ± 0.01 mg Ag/L, respectively. Dissolution and bioavailability of Ag from NWs and nanospheres, analyzed with AAS or Ag-sensor bacteria, respectively, suggested that the toxic effects were caused by solubilized Ag(+) ions. Moreover, the antibacterial activities of Ag NWs suspension and its ultracentrifuged particle-free supernatant were equal. The latter indicated that the toxic effects of ~80-100 nm Ag nanostructures to Escherichia coli were solely dependent on their dissolution and no shape-induced/related effects were observed. Yet, additional nanospecific effects could come into play in case of smaller nanosilver particles.
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