ArticleBioMed research international2013
End-systolic elastance and ventricular-arterial coupling reserve predict cardiac events in patients with negative stress echocardiography.
Article in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Non-invasive myocardial work analysis in normal, at-risk for heart failure and heart failure patients during stress testing-a systematic review: a joint session with the Romanian Society of Cardiology (part III).Heart failure reviews · 2026Pooled it
- Trial
- Dynamics of ventriculo-arterial coupling and peripheral tissue perfusion during early resuscitation of septic shock.Annals of intensive care · 2026Article
- Stress echocardiography in heart failure patients: additive value and caveats.Heart failure reviews · 2024Review
- Correlation of Noninvasive Cardiac MRI Measures of Left Ventricular Myocardial Function and Invasive Pressure-Volume Parameters in a Porcine Ischemia-Reperfusion Model.Radiology. Cardiothoracic imaging · 2024Article
- Development and Clinical Application of Left Ventricular-Arterial Coupling Non-Invasive Assessment Methods.Journal of cardiovascular development and disease · 2024Review
- Left Ventricular-Arterial Coupling as an Independent Predictor of Adverse Events in Young Patients with ST Elevation Myocardial Infarction-A 3D Echocardiographic Study.Biomedicines · 2024Article
- Mild hypothermia attenuates ischaemia/reperfusion injury: insights from serial non-invasive pressure-volume loops.Cardiovascular research · 2023Article
- Acausal Modelling of Advanced-Stage Heart Failure and the Istanbul Heart Ventricular Assist Device Support with Patient Data.Cardiovascular engineering and technology · 2023Article
- Dose-consistent dynamic SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- ABCDEG Stress Echocardiography in Aortic Stenosis.Diagnostics (Basel, Switzerland) · 2023Review
- Acute Kidney Injury in Critically-Ill COVID-19 Patients.Journal of clinical medicine · 2022Article
- Pressure-volume relationship by pharmacological stress cardiovascular magnetic resonance.The international journal of cardiovascular imaging · 2022Article
- Pralidoxime improves the hemodynamics and survival of rats with peritonitis-induced sepsis.PloS one · 2021Article
- Revisiting the relationship between left ventricular ejection fraction and ventricular-arterial coupling.ESC heart failure · 2020Review
- Understanding ventriculo-arterial coupling.Annals of translational medicine · 2020Review
- Heart failure with preserved ejection fraction: the missing pieces in diagnostic imaging.Heart failure reviews · 2020Review
- Prenatal hypoxia affected endothelium-dependent vasodilation in mesenteric arteries of aged offspring via increased oxidative stress.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- The value of a simplified approach to end-systolic volume measurement for assessment of left ventricular contractile reserve during stress-echocardiography.The international journal of cardiovascular imaging · 2019Article
- Drop-off in positivity rate of stress echocardiography based on regional wall motion abnormalities over the last three decades.The international journal of cardiovascular imaging · 2019Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA maximal negative stress echo identifies a low-risk subset for coronary events. However, the potentially prognostically relevant information on cardiovascular hemodynamics for heart-failure-related events is unsettled. Aim of this study was to assess the prognostic value of stress-induced variation in cardiovascular hemodynamics in patients with negative stress echocardiography.
methodsWe enrolled 891 patients (593 males mean age 63 ± 12, ejection fraction 48 ± 17%), with negative (exercise 172, dipyridamole 482, and dobutamine 237) stress echocardiography result. During stress we assessed left ventricular end-systolic elastance index (E(LV)I), ventricular arterial coupling (VAC) indexed by the ratio of the E(LV)I to arterial elastance index (E aI), systemic vascular resistance (SVR), and pressure-volume area (PVA). Changes from rest to peak stress (reserve) were tested as predictors of main outcome measures: combined death and heart failure hospitalization.
resultsDuring a median followup of 19 months (interquartile range 8-36), 50 deaths and 84 hospitalization occurred. Receiver-operating-characteristic curves identified as best predictors E(LV)I reserve for exercise (AUC = 0.871) and dobutamine (AUC = 0.848) and VAC reserve (AUC = 0.696) for dipyridamole.
conclusionsPatients with negative stress echocardiography may experience an adverse outcome, which can be identified by assessment of E(LV)I reserve and VAC reserve during stress echo.
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