Evidence map›Paper›PMID 24023700›Full record

ArticlePloS one2013

HPV prevalence among women from Appalachia: results from the CARE project.

Paul L Reiter, Mira L Katz, Mack T Ruffin, Erinn M Hade, Cecilia R DeGraffenreid, Divya A Patel, Electra D Paskett, Elizabeth R Unger

Erratum issued Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT02113514 (Community Awareness, Resources and Education), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02113514 completednot on this map

Community Awareness, Resources and Education (CARE I): Project 3

TypeobservationalSponsorOhio State University Comprehensive Cancer CenterRan2005 to 2009Enrolled2,394ConditionsCervical Abnormality
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Results of a Multilevel Intervention Trial to Increase Human Papillomavirus (HPV) Vaccine Uptake among Adolescent Girls.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2016
    Trial
  3. Article
  4. Article
  5. Article
  6. A Multi-level Model to Understand Cervical Cancer Disparities in Appalachia.Cancer prevention research (Philadelphia, Pa.) · 2020
    Article
  7. Article
  8. Article
  9. Effects of an Education Intervention about HPV Self-Testing for Healthcare Providers and Staff.Journal of cancer education : the official journal of the American Association for Cancer Education · 2018
    Article
  10. Review
  11. Article
  12. Review
  13. Cervical cancer worry and screening among appalachian women.The journal of primary prevention · 2015
    Article
  14. Fatalistic beliefs and completion of the HPV vaccination series among a sample of young Appalachian Kentucky women.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2015
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Paul L ReiterDivision of Cancer Prevention and Control, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America ; Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America ; College of Public Health, The Ohio State University, Columbus, Ohio, United States of America.
Mira L Katz
Mack T Ruffin
Erinn M Hade
Cecilia R DeGraffenreid
Divya A Patel
Electra D Paskett
Elizabeth R Unger
The Ohio State University · USCenters for Disease Control and Prevention · USMichigan United · USUniversity of Michigan–Ann Arbor · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
TRAINING AND CAREER DEVELOPMENTP50CA105632 · NCI · OHIO STATE UNIVERSITY · PI PASKETT, ELECTRA D. · 2003 to 2016
$17.2M
NCI NIH HHS P30 CA016058NCI NIH HHS P30CA016058NCI NIH HHS P50 CA105632NCI NIH HHS P50CA105632
6 · The paper itself

Abstract

backgroundCervical cancer incidence and mortality rates are high among women from Appalachia, yet data do not exist on human papillomavirus (HPV) prevalence among these women. We examined the prevalence of genital HPV among Appalachian women and identified correlates of HPV detection.

methodsWe report data from a case-control study conducted between January 2006 and December 2008 as part of the Community Awareness, Resources, and Education (CARE) Project. We examined HPV prevalence among 1116 women (278 women with abnormal Pap tests at study entry [cases], 838 women with normal Pap tests [controls]) from Appalachian Ohio. Analyses used multivariable logistic regression to identify correlates of HPV detection.

resultsThe prevalence of HPV was 43.1% for any HPV type, 33.5% for high-risk HPV types, 23.4% for low-risk HPV types, and 12.5% for vaccine-preventable HPV types. Detection of any HPV type was more common among women who were ages 18-26 (OR = 2.09, 95% CI: 1.26-3.50), current smokers (OR = 1.86, 95% CI: 1.26-2.73), had at least five male sexual partners during their lifetime (OR = 2.28, 95% CI: 1.56-3.33), or had multiple male sexual partners during the last year (OR = 1.98, 95% CI: 1.25-3.14). Similar correlates were identified for detection of a high-risk HPV type.

conclusionsHPV was prevalent among Appalachian women, with many women having a high-risk HPV type detected. Results may help explain the high cervical cancer rates observed among Appalachian women and can help inform future cervical cancer prevention efforts in this geographic region.

Indexed as

Health Knowledge, Attitudes, PracticeAdolescentAdultAppalachian RegionFemaleHumansMaleNutrition SurveysPapillomaviridaePapillomavirus InfectionsPrevalenceRisk FactorsYoung Adult

Identifiers

PMID24023700
PMCPMC3758277
OpenAlexW2030327420

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.