ArticleMediators of inflammation2013
Impact of the body mass on complications and outcome in multiple trauma patients: what does the weight weigh?
Article in Mediators of inflammation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- BMI is independently associated with ARDS, sepsis and multiorgan failure after major trauma-results of a high-volume retrospective observational cohort study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2026Observational
- Impact of alcohol consumption on outcomes and potential of immune biomarkers for postoperative complications in trauma patients.Frontiers in immunology · 2025Article
- The Impact of Body Mass Composition on Outcome in Multiple Traumatized Patients-Results from the Fourth Thoracic and Third Lumbar Vertebrae: A Single-Center Retrospective Observational Study.Journal of clinical medicine · 2023Article
- Nomogram predicts CR-POPF in open central pancreatectomy patients with benign or low-grade malignant pancreatic neoplasms.Frontiers in oncology · 2022Article
- The Effect of Fat Distribution on the Inflammatory Response of Multiple Trauma Patients-A Retrospective Study.Life (Basel, Switzerland) · 2021Article
- The Impact of Obesity on Critical Illnesses.Shock (Augusta, Ga.) · 2021Review
- Impact of pathologic body composition assessed by CT-based anthropometric measurements in adult patients with multiple trauma: a retrospective analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2021Article
- Impact of Chest Trauma and Overweight on Mortality and Outcome in Severely Injured Patients.Journal of clinical medicine · 2020Article
- Influence of Obesity on the Organization of the Extracellular Matrix and Satellite Cell Functions After Combined Muscle and Thorax Trauma in C57BL/6J Mice.Frontiers in physiology · 2020Article
- Body mass index interaction effects with hyperglycemia and hypocholesterolemia modify blunt traumatic brain injury outcomes: a retrospective study.International journal of burns and trauma · 2020Article
- Making sense of gut feelings in the traumatic brain injury pathogenesis.Neuroscience and biobehavioral reviews · 2019Review
- OBESITY AND CRITICAL ILLNESS: INSIGHTS FROM ANIMAL MODELS.Shock (Augusta, Ga.) · 2016Review
- Traumatic injuries among adult obese patients in southern Taiwan: a cross-sectional study based on a trauma registry system.BMC public health · 2016Article
- Obesity and clotting: Body mass index independently contributes to hypercoagulability after injury.The journal of trauma and acute care surgery · 2015Article
- Mechanism of injury and treatment of trauma-associated acute compartment syndrome of the foot.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2014Article
- [Quality of life after multiple trauma].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is known as an independent risk factor for various morbidities. The influence of an increased body mass index (BMI) on morbidity and mortality in critically injured patients has been investigated with conflicting results. To verify the impact of weight disorders in multiple traumatized patients, 586 patients with an injury severity score >16 points treated at a level I trauma center between 2005 and 2011 were differentiated according to the BMI and analyzed regarding morbidity and outcome. Plasma levels of interleukin- (IL-) 6 and C-reactive protein (CRP) were measured during clinical course to evaluate the inflammatory response to the "double hit" of weight disorders and multiple trauma. In brief, obesity was the highest risk factor for development of a multiple organ dysfunction syndrome (MODS) (OR 4.209, 95%-CI 1.515-11.692) besides injury severity (OR 1.054, 95%-CI 1.020-1.089) and APACHE II score (OR 1.059, 95%-CI 1.001-1.121). In obese patients as compared to those with overweight, normal weight, and underweight, the highest levels of CRP were continuously present while increased systemic IL-6 levels were found until day 4. In conclusion, an altered posttraumatic inflammatory response in obese patients seems to determine the risk for multiple organ failure after severe trauma.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.