Evidence map›Paper›PMID 24022248›Full record

ArticleDementia and geriatric cognitive disorders2013

Caregiver burden in frontotemporal degeneration and corticobasal syndrome.

Nicole Armstrong, Nicole Schupf, Jordan Grafman, Edward D Huey

Open access · greenAbstract read
In one paragraph

Article in Dementia and geriatric cognitive disorders, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Altered reward processing underpins emotional apathy in dementia.Cognitive, affective & behavioral neuroscience · 2023
    Article
  5. Article
  6. Towards Defining the Neuroanatomical Basis of Late-Onset Psychiatric Symptoms.Journal of geriatric psychiatry and neurology · 2022
    Review
  7. The contribution of behavioral features to caregiver burden in FTLD spectrum disorders.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022
    Article
  8. Caregiver strain in progressive supranuclear palsy and corticobasal syndromes.Journal of neural transmission (Vienna, Austria : 1996) · 2021
    Article
  9. Article
  10. A Critical Review of Behavioral and Emotional Disinhibition.The Journal of nervous and mental disease · 2020
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nicole ArmstrongDepartment of Epidemiology, Mailman School of Public Health, New York, N.Y., USA.
Nicole Schupf
Jordan Grafman
Edward D Huey
National Institutes of Health · USColumbia University · US

Funding

Satellite Diagnostic and Treatment Clinic CoreP50AG008702 · NIA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI DE JAGER, PHILIP L · 1989 to 2019
$46.3M
EPIDEMIOLOGY AND BIOSTATISTICS OF AGINGT32AG000247 · NIA · JOHNS HOPKINS UNIVERSITY · PI Karen J. Bandeen-Roche · 1996 to 2026
$13.2M
Examination of the earliest symptoms and biomarkers of FTLD MAPT carriersR01NS076837 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI COSENTINO, STEPHANIE ANN, HUEY, EDWARD D · 2012 to 2016
$2.5M
Investigation of the dopamine system in frontotemporal dementiaR00NS060766 · NINDS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI HUEY, EDWARD D · 2009 to 2011
$732k
NIA NIH HHS P50 AG008702NIA NIH HHS T32 AG000247NINDS NIH HHS R00 NS060766NINDS NIH HHS R01 NS076837
6 · The paper itself

Abstract

BACKGROUND AND

aimsCaregiver stress is often a serious problem when caring for a patient with frontal lobe dysfunction.

methodsA total of 102 caregivers of both patients with frontotemporal degeneration and corticobasal syndrome completed the Frontal Systems Behavior Scale (FrSBe) and the Zarit Burden Interview (ZBI). To analyze the association between apathy or disinhibition (or both) and caregiver burden, the effects of the total FrSBe and the apathy and disinhibition subscales of the FrSBE on the total ZBI score were assessed with logistic regressions and t tests.

resultsTotal FrSBE score and the apathy FrSBE subscore predicted caregiver burden. Apathy occurred without disinhibition, and the two occurred together, but disinhibition without apathy was very rare.

conclusionsDisinhibition without apathy occurred very rarely. Apathy was more associated with caregiver burden than disinhibition.

Indexed as

Cost of IllnessAdaptation, PsychologicalApathyCaregiversExecutive FunctionFemaleFrontotemporal DementiaHumansLogistic ModelsMaleNeurodegenerative DiseasesOccupational DiseasesStress, PsychologicalSurveys and QuestionnairesSyndrome

Identifiers

PMID24022248
PMCPMC4484601
OpenAlexW2007984289

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.