Evidence map›Paper›PMID 24021679›Full record

Trial reportStroke2013

The Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study protocol.

Daniel Woo, Jonathan Rosand, Chelsea Kidwell, Jacob L McCauley, Jennifer Osborne, Mark W Brown, Sandra E West, Eric W Rademacher, Salina Waddy, Jamie N Roberts and 23 more

Open access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Stroke, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 7 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 7 syntheses or guidelines pooled it, 116 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Guideline
  7. Pooled it
  8. Trial
  9. Trial
  10. Article
  11. Article
  12. Genetics of intracerebral hemorrhage.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Article
  19. Article
  20. Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 4 institutions in 1 country.

Daniel WooFrom the University of Cincinnati, College of Medicine, OH (D.W., J.O., M.F.); Massachusetts General Hospital, Harvard Medical School, Boston, MA (J.R.); Department of Neurology, Georgetown University Medical Center, Washington, DC (C.K.); John P. Hussman Institute for Human Genomics, University of Miami, FL (J.L.M., S.E.W.); Department of Biostatistical Sciences, Wake Forest University School of Medicine, Winston-Salem, NC (M.W.B., C.D.L.); Institute for Policy Research, University of Cincinnati, OH (E.W.R.); National Institute of Neurological Disorders and Stroke, Bethesda, MD (S.W., J.N.R.); University of Miami, Miller School of Medicine, FL (S.K., R.I.S.); University of Texas Medical School-Houston, TX (N.R.G., R.M.); University of Southern California, Neurocritical Care and Stroke Division, Los Angeles, CA (G.S.); University of Maryland, Baltimore Veterans Administration Medical Center, MD (S.K.); University of Texas Health Science Center at San Antonio, TX (L.B., F.J., A.L.); Emory University, Grady Memorial Hospital, Atlanta, GA (M.F.); University of Illinois at Chicago Medical Center, IL (F.D.T.); Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX (C.E.H.); Columbia University, New York, NY (M.S.V.E.); University of Arizona, Tucson, AZ (B.C.); St. Luke's-Roosevelt Hospital Center, New York, NY (J.Y.C.); University of California San Francisco, Fresno, CA (T.W.); University of New Mexico, Albuquerque, NM (M.M.); Department of Anesthesiology, Duke University, Durham, NC (M.L.J.); University of California, Los Angeles, CA (L.K.A.); Department of Neurology and Public Health Sciences, University of Virginia, Charlottesville, VA (B.B.W.); and Department of Neurology, University of Maryland School of Medicine, Baltimore, MD (T.W.).
Jonathan Rosand
Chelsea Kidwell
Jacob L McCauley
Jennifer Osborne
Mark W Brown
Sandra E West
Eric W Rademacher
Salina Waddy
Jamie N Roberts
Sebastian Koch
Nicole R Gonzales
Gene Sung
Steven J Kittner
Lee Birnbaum
Michael Frankel
Fernando Daniel Testai
Christiana E Hall
Mitchell S V Elkind
Matthew Flaherty
Bruce Coull
Ji Y Chong
Tanya Warwick
Marc Malkoff
Michael L James
Latisha K Ali
Bradford B Worrall
Floyd Jones
Tiffany Watson
Anne Leonard
Rebecca Martinez
Ralph I Sacco
Carl D Langefeld
Emory University · USNational Institutes of Health · USGeorgetown University · USUniversity of Maryland, Baltimore · US

Funding

Ethnic/Racial Variation in Intracerebral Hemorrhage (ERICH)U01NS069763 · NINDS · UNIVERSITY OF CINCINNATI · PI ANDERSON, CHRISTOPHER DAVID, DEMEL, STACIE · 2010 to 2024
$34.2M
Cincinnati Neuroscience Clinical Trials Research Center (CinciNEXT)U10NS077311 · NINDS · UNIVERSITY OF CINCINNATI · PI GLAUSER, TRACY A, WOO, DANIEL · 2011 to 2017
$2.1M
NINDS NIH HHS U-01-NS069763NINDS NIH HHS U01 NS069763
6 · The paper itself

Abstract

background and purposeEpidemiological studies of intracerebral hemorrhage (ICH) have consistently demonstrated variation in incidence, location, age at presentation, and outcomes among non-Hispanic white, black, and Hispanic populations. We report here the design and methods for this large, prospective, multi-center case-control study of ICH.

methodsThe Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study is a multi-center, prospective case-control study of ICH. Cases are identified by hot-pursuit and enrolled using standard phenotype and risk factor information and include neuroimaging and blood sample collection. Controls are centrally identified by random digit dialing to match cases by age (±5 years), race, ethnicity, sex, and metropolitan region.

resultsAs of March 22, 2013, 1655 cases of ICH had been recruited into the study, which is 101.5% of the target for that date, and 851 controls had been recruited, which is 67.2% of the target for that date (1267 controls) for a total of 2506 subjects, which is 86.5% of the target for that date (2897 subjects). Of the 1655 cases enrolled, 1640 cases had the case interview entered into the database, of which 628 (38%) were non-Hispanic black, 458 (28%) were non-Hispanic white, and 554 (34%) were Hispanic. Of the 1197 cases with imaging submitted, 876 (73.2%) had a 24 hour follow-up CT available. In addition to CT imaging, 607 cases have had MRI evaluation.

conclusionsThe ERICH study is a large, case-control study of ICH with particular emphasis on recruitment of minority populations for the identification of genetic and epidemiological risk factors for ICH and outcomes after ICH.

Indexed as

Black or African AmericanCerebral HemorrhageDatabases, FactualHispanic or LatinoWhite PeopleAdolescentAdultAgedAged, 80 and overCase-Control StudiesFemaleHumansMaleMiddle AgedProspective StudiesSex Factorscerebral hemorrhagegeneticsgenomicshypertensionminority groupsrisk factorsstroke

Identifiers

PMID24021679
PMCPMC3873723
OpenAlexW2118775574

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.