ArticleBMC pediatrics2013
Addition of SNAP to perinatal risk factors improves the prediction of bronchopulmonary dysplasia or death in critically ill preterm infants.
Article in BMC pediatrics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- nSOFA scores predict prolonged mechanical ventilation in neonatal respiratory distress syndrome: a retrospective cohort study.BMC pediatrics · 2025Article
- [Development of dynamic multi-time-point clinical prediction models for bronchopulmonary dysplasia in preterm infants with gestational age < 32 weeks].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Article
- Prevalence and Factors Affecting Appropriate Inhaler Use in Elderly Patients with Chronic Obstructive Pulmonary Disease: A Prospective Study.Journal of clinical medicine · 2023Article
- Clinical and polysomnographic characteristics in adults referred to the sleep laboratory: a single-center study.Qatar medical journal · 2022Article
- Is Academic Achievement Related to Mediterranean Diet, Substance Use and Social-Cognitive Factors: Findings from Lebanese Adolescents.Nutrients · 2020Article
- The effectiveness of urinary TIMP-2 and IGFBP-7 in predicting acute kidney injury in critically ill neonates.Pediatric research · 2020Article
- Increased Frequency of Skin-to-Skin Contact Is Associated with Enhanced Vagal Tone and Improved Health Outcomes in Preterm Neonates.American journal of perinatology · 2019Article
- Subclinical acute kidney injury is associated with adverse outcomes in critically ill neonates and children.Critical care (London, England) · 2018Article
- Preterm Stress Behaviors, Autonomic Indices, and Maternal Perceptions of Infant Colic.Advances in neonatal care : official journal of the National Association of Neonatal Nurses · 2018Article
- Article
- Early Heart Rate Characteristics Predict Death and Morbidities in Preterm Infants.The Journal of pediatrics · 2016Article
- Biomarkers for Bronchopulmonary Dysplasia in the Preterm Infant.Frontiers in pediatrics · 2016Review
- Disrupted lung development and bronchopulmonary dysplasia: opportunities for lung repair and regeneration.Current opinion in pediatrics · 2014Review
- Derivation of a clinical decision rule for predictive factors for the development of pharyngocutaneous fistula postlaryngectomy.Brazilian journal of otorhinolaryngologyArticle
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8 authors.
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Abstract
backgroundBronchopulmonary dysplasia (BPD) is the most common serious pulmonary morbidity in premature infants. The score for neonatal acute physiology (SNAP) is a physiologic severity index for neonatal intensive care and correlates well with neonatal mortality and clinical outcomes. The prognostic value of the SNAP score for BPD in preterm infants remains to be clarified. The aim of the study was to determine whether SNAP can predict the development of BPD or death, and to investigate the contribution of SNAP to the predictive accuracy of other potential perinatal risk factors for the adverse outcome in critically ill preterm infants.
methodsWe conducted a study in 160 critically ill preterm infants with less than 33 gestational weeks. The original SNAP score was prospectively calculated based on 28 items collected during the first 24 hours of admission. The potential perinatal risk factors were assessed during the first 72 hours of life. Major outcome measures were BPD and mortality before the time of BPD screening.
resultsOf the 160 infants, 17 died and 41 developed BPD. The SNAP score was significantly associated with BPD or death (odds ratio [OR] =1.28; 95% confidence interval [CI], 1.16-1.41; p <0.001), even after adjustment for gestational age (OR =1.27; 95% CI, 1.13-1.41; p <0.001). High SNAP score was an independent predictor of BPD or death (area under the curve [AUC] =0.78; 95% CI, 0.70-0.85; p <0.001), with additional predictive value when combined with other perinatal risk factors. Multivariate regression analysis resulted in a final model, including SNAP, gestational age, apnea of prematurity, patent ductus arteriosus, and surfactant use as independent risk factors, with a higher predictive accuracy compared with individual components (AUC =0.92; 95% CI, 0.87-0.96; p <0.001).
conclusionsSNAP is associated with adverse outcome of BPD or death. High SNAP scores are predictive of BPD or death in critically ill preterm infants, and add prognostic value to other perinatal risk factors.
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