ArticlePLoS biology2013
Photoperiodic regulation of flowering time through periodic histone deacetylation of the florigen gene FT.
Article in PLoS biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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42 citing papers in PubMed, 83 citations in OpenAlex.
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- A pair of readers of histone H3K4 methylation recruit Polycomb repressive complex 2 to regulate photoperiodic flowering.Nature communications · 2025Article
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- Regulation of Flowering Time by Environmental Factors in Plants.Plants (Basel, Switzerland) · 2023Review
- MtING2 encodes an ING domain PHD finger protein which affects Medicago growth, flowering, global patterns of H3K4me3, and gene expression.The Plant journal : for cell and molecular biology · 2022Article
- Molecular Genetic Understanding of Photoperiodic Regulation of Flowering Time inInternational journal of molecular sciences · 2021Review
- PRMT6 physically associates with nuclear factor Y to regulate photoperiodic flowering inaBIOTECH · 2021Article
- Rice and Arabidopsis homologs of yeast CHROMOSOME TRANSMISSION FIDELITY PROTEIN 4 commonly interact with Polycomb complexes but exert divergent regulatory functions.The Plant cell · 2021Article
- The diverse and unanticipated roles of histone deacetylase 9 in coordinating plant development and environmental acclimation.Journal of experimental botany · 2020Review
- Rice homolog of Sin3-associated polypeptide 30, OsSFL1, mediates histone deacetylation to regulate flowering time during short days.Plant biotechnology journal · 2020Article
- Genetic and Epigenetic Understanding of the Seasonal Timing of Flowering.Plant communications · 2020Review
- HISTONE DEACETYLASE 9 stimulates auxin-dependent thermomorphogenesis inProceedings of the National Academy of Sciences of the United States of America · 2019Article
- FT Modulates Genome-Wide DNA-Binding of the bZIP Transcription Factor FD.Plant physiology · 2019Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The developmental transition from a vegetative to a reproductive phase (i.e., flowering) is timed by the seasonal cue day length or photoperiod in many plant species. Through the photoperiod pathway, inductive day lengths trigger the production of a systemic flowering signal, florigen, to provoke the floral transition. FLOWERING LOCUS T (FT), widely conserved in angiosperms, is a major component of the mobile florigen. In the long-day plant Arabidopsis, FT expression is rhythmically activated by the output of the photoperiod pathway CONSTANS (CO), specifically at the end of long days. How FT expression is modulated at an adequate level in response to the long-day cue to set a proper flowering time remains unknown. Here, we report a periodic histone deacetylation mechanism for the photoperiodic modulation of FT expression. We have identified a plant-unique core structural component of an Arabidopsis histone deacetylase (HDAC) complex. In long days, this component accumulates at dusk, and is recruited by a MADS-domain transcription factor to the FT locus specifically at the end of the day, leading to periodic histone deacetylation of FT chromatin at dusk. Furthermore, we found that at the end of long days CO activity not only activates FT expression but also enables HDAC-activity recruitment to FT chromatin to dampen the level of FT expression, and so prevent precocious flowering in response to the inductive long-day cue. These results collectively reveal a periodic histone deacetylation mechanism for the day-length control of flowering time in higher plants.
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