Evidence map›Paper›PMID 24019556›Full record

ArticlePesticide biochemistry and physiology2013

Diversity and Convergence of Sodium Channel Mutations Involved in Resistance to Pyrethroids.

Frank D Rinkevich, Yuzhe Du, Ke Dong

Open access · greenAbstract read
In one paragraph

Article in Pesticide biochemistry and physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 322 citations in OpenAlex.

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  9. F1534SFrontiers in cellular and infection microbiology · 2026
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65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Frank D RinkevichDepartment of Entomology, Genetics and Neuroscience Programs, Michigan State University, East Lansing, MI 48824-1115 USA.
Yuzhe Du
Ke Dong
Michigan State University · US

Funding

Molecular mechanisms of action and resistance of sodium channel-targeting insectiR01GM057440 · NIGMS · MICHIGAN STATE UNIVERSITY · PI DONG, KE, HUGHSON, FREDERICK M · 1999 to 2023
$5.4M
Role of the DSC1 family of cation channels in insect neurophysiology and neurotoxR01GM080255 · NIGMS · MICHIGAN STATE UNIVERSITY · PI DONG, KE, WU, CHUN-FANG · 2009 to 2012
$1.1M
NIGMS NIH HHS R01 GM057440NIGMS NIH HHS R01 GM080255
6 · The paper itself

Abstract

Pyrethroid insecticides target voltage-gated sodium channels, which are critical for electrical signaling in the nervous system. The intensive use of pyrethroids in controlling arthropod pests and disease vectors has led to many instances of pyrethroid resistance around the globe. In the past two decades, studies have identified a large number of sodium channel mutations that are associated with resistance to pyrethroids. The purpose of this review is to summarize both common and unique sodium channel mutations that have been identified in arthropod pests of importance to agriculture or human health. Identification of these mutations provides valuable molecular markers for resistance monitoring in the field and helped the discovery of the elusive pyrethroid receptor site(s) on the sodium channel.

Identifiers

PMID24019556
PMCPMC3765034
OpenAlexW1994017019

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.